Social hierarchy modulates drug reinforcement and protein phosphorylation in the nucleus accumbens

Social hierarchy modulates drug reinforcement and protein phosphorylation in the nucleus accumbens

IntroductionDrug reinforcement, a form of behavioral plasticity in which behavioral changes happen in response to a reinforcing drug, would finally lead to drug addiction after chronical drug exposure. Drug reinforcement is affected by genetic and environmental factors. Social hierarchy has been rep...

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Bibliographic Details
Main Authors: Liang Xu, Ruiyi Zhou, Jiafeng Zhong, Yina Huang, Yingjie Zhu, Wei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
social hierarchy
drug reinforcement
phosphoproteomics
drug addiction
HDAC4
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1537131/full
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