Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring
The phase transitions of binary lipid mixtures are studied by a combination of Peltier-element-based adiabatic scanning calorimetry (pASC) and quartz crystal microbalance with dissipation monitoring (QCM-D). pASC, a novel type of calorimeter, provides valuable and unambiguous information on the heat...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Advances in Condensed Matter Physics |
| Online Access: | http://dx.doi.org/10.1155/2015/479318 |
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| author | P. Losada-Pérez N. Mertens B. de Medio-Vasconcelos E. Slenders J. Leys M. Peeters B. van Grinsven J. Gruber C. Glorieux H. Pfeiffer P. Wagner J. Thoen |
| author_facet | P. Losada-Pérez N. Mertens B. de Medio-Vasconcelos E. Slenders J. Leys M. Peeters B. van Grinsven J. Gruber C. Glorieux H. Pfeiffer P. Wagner J. Thoen |
| author_sort | P. Losada-Pérez |
| collection | DOAJ |
| description | The phase transitions of binary lipid mixtures are studied by a combination of Peltier-element-based adiabatic scanning calorimetry (pASC) and quartz crystal microbalance with dissipation monitoring (QCM-D). pASC, a novel type of calorimeter, provides valuable and unambiguous information on the heat capacity and the enthalpy, whereas QCM-D is proposed as a genuine way of determining phase diagrams by analysing the temperature dependence of the viscosity. Two binary mixtures of phospholipids with the same polar head and differing in the alkyl chain length, DMPC + DPPC and DMPC + DSPC, are discussed. Both techniques give consistent phase diagrams, which compare well with literature results, showing their capability to map the phase behaviour of pure lipids as well as lipid mixtures. This work can be considered as a departure point for further investigations on more complex lipid mixtures displaying relevant phases such as the liquid-ordered phase and solid-lipid interfaces with biologically functional importance. |
| format | Article |
| id | doaj-art-d1278884e0274b59af646a09fa8d17c7 |
| institution | DOAJ |
| issn | 1687-8108 1687-8124 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Condensed Matter Physics |
| spelling | doaj-art-d1278884e0274b59af646a09fa8d17c72025-08-20T03:19:38ZengWileyAdvances in Condensed Matter Physics1687-81081687-81242015-01-01201510.1155/2015/479318479318Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation MonitoringP. Losada-Pérez0N. Mertens1B. de Medio-Vasconcelos2E. Slenders3J. Leys4M. Peeters5B. van Grinsven6J. Gruber7C. Glorieux8H. Pfeiffer9P. Wagner10J. Thoen11Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, BelgiumLaboratorium voor Akoestiek en Thermische Fysica, Departement Natuurkunde en Sterrenkunde, KU Leuven, Celestijnenlaan 200D Bus 2416, 3001 Leuven, BelgiumInstituto de Química, Universidade de São Paulo, 748 Av. Prof. Lineu Prestes, 05508-000 São Paulo, SP, BrazilLaboratorium voor Akoestiek en Thermische Fysica, Departement Natuurkunde en Sterrenkunde, KU Leuven, Celestijnenlaan 200D Bus 2416, 3001 Leuven, BelgiumLaboratorium voor Akoestiek en Thermische Fysica, Departement Natuurkunde en Sterrenkunde, KU Leuven, Celestijnenlaan 200D Bus 2416, 3001 Leuven, BelgiumInstitute for Materials Research IMO, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, BelgiumMaastricht Science Programme, Maastricht University, 6200 MD Maastricht, NetherlandsInstituto de Química, Universidade de São Paulo, 748 Av. Prof. Lineu Prestes, 05508-000 São Paulo, SP, BrazilLaboratorium voor Akoestiek en Thermische Fysica, Departement Natuurkunde en Sterrenkunde, KU Leuven, Celestijnenlaan 200D Bus 2416, 3001 Leuven, BelgiumStructurele Materialen, Departement Materiaalkunde, KU Leuven, Kasteelpark Arenberg 44 Bus 2450, 3001 Leuven, BelgiumInstitute for Materials Research IMO, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, BelgiumLaboratorium voor Akoestiek en Thermische Fysica, Departement Natuurkunde en Sterrenkunde, KU Leuven, Celestijnenlaan 200D Bus 2416, 3001 Leuven, BelgiumThe phase transitions of binary lipid mixtures are studied by a combination of Peltier-element-based adiabatic scanning calorimetry (pASC) and quartz crystal microbalance with dissipation monitoring (QCM-D). pASC, a novel type of calorimeter, provides valuable and unambiguous information on the heat capacity and the enthalpy, whereas QCM-D is proposed as a genuine way of determining phase diagrams by analysing the temperature dependence of the viscosity. Two binary mixtures of phospholipids with the same polar head and differing in the alkyl chain length, DMPC + DPPC and DMPC + DSPC, are discussed. Both techniques give consistent phase diagrams, which compare well with literature results, showing their capability to map the phase behaviour of pure lipids as well as lipid mixtures. This work can be considered as a departure point for further investigations on more complex lipid mixtures displaying relevant phases such as the liquid-ordered phase and solid-lipid interfaces with biologically functional importance.http://dx.doi.org/10.1155/2015/479318 |
| spellingShingle | P. Losada-Pérez N. Mertens B. de Medio-Vasconcelos E. Slenders J. Leys M. Peeters B. van Grinsven J. Gruber C. Glorieux H. Pfeiffer P. Wagner J. Thoen Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring Advances in Condensed Matter Physics |
| title | Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring |
| title_full | Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring |
| title_fullStr | Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring |
| title_full_unstemmed | Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring |
| title_short | Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring |
| title_sort | phase transitions of binary lipid mixtures a combined study by adiabatic scanning calorimetry and quartz crystal microbalance with dissipation monitoring |
| url | http://dx.doi.org/10.1155/2015/479318 |
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