Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis
Conclusion: This study is the first to identify MAPK13 and POR as potential drug targets for sarcoidosis. In addition, molecular docking preliminarily identified potential therapeutic compounds targeting these proteins, suggesting avenues for future experimental validation and the potential developm...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/ijcp/3094370 |
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| _version_ | 1849716708482220032 |
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| author | Xun Yang Hao Jiang Xiaoyun Li |
| author_facet | Xun Yang Hao Jiang Xiaoyun Li |
| author_sort | Xun Yang |
| collection | DOAJ |
| description | Conclusion: This study is the first to identify MAPK13 and POR as potential drug targets for sarcoidosis. In addition, molecular docking preliminarily identified potential therapeutic compounds targeting these proteins, suggesting avenues for future experimental validation and the potential development of targeted therapies. |
| format | Article |
| id | doaj-art-d1173bfbbc4446b3a113408367cd61a5 |
| institution | DOAJ |
| issn | 1742-1241 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Clinical Practice |
| spelling | doaj-art-d1173bfbbc4446b3a113408367cd61a52025-08-20T03:12:54ZengWileyInternational Journal of Clinical Practice1742-12412025-01-01202510.1155/ijcp/3094370Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics AnalysisXun Yang0Hao Jiang1Xiaoyun Li2Department of Respiratory and Critical Care MedicineDepartment of Otorhinolaryngology-Head and Neck SurgeryDepartment of PharmacyConclusion: This study is the first to identify MAPK13 and POR as potential drug targets for sarcoidosis. In addition, molecular docking preliminarily identified potential therapeutic compounds targeting these proteins, suggesting avenues for future experimental validation and the potential development of targeted therapies.http://dx.doi.org/10.1155/ijcp/3094370 |
| spellingShingle | Xun Yang Hao Jiang Xiaoyun Li Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis International Journal of Clinical Practice |
| title | Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis |
| title_full | Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis |
| title_fullStr | Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis |
| title_full_unstemmed | Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis |
| title_short | Oxidative Stress-Related Targets POR and MAPK13 Elucidated for Sarcoidosis Therapy Through Multiomics Analysis |
| title_sort | oxidative stress related targets por and mapk13 elucidated for sarcoidosis therapy through multiomics analysis |
| url | http://dx.doi.org/10.1155/ijcp/3094370 |
| work_keys_str_mv | AT xunyang oxidativestressrelatedtargetsporandmapk13elucidatedforsarcoidosistherapythroughmultiomicsanalysis AT haojiang oxidativestressrelatedtargetsporandmapk13elucidatedforsarcoidosistherapythroughmultiomicsanalysis AT xiaoyunli oxidativestressrelatedtargetsporandmapk13elucidatedforsarcoidosistherapythroughmultiomicsanalysis |