Ischemic and Pharmacological Preconditioning (part 2)
This paper is the second part of an overview dealing with experimental and clinical studies in ischemic and pharmacological preconditioning. It considers the possibilities of practically using the available knowledge on the mechanisms of preconditioning, the interaction of agents from different grou...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2012-02-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/247 |
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| author | V. V. Likhvantsev V. V. Moroz O. A. Grebenchikov Yu. I., Gorokhovatsky Yu. V. Zarzhetsky S. S. Timoshin D. I. Levikov V. L. Shaibakova |
| author_facet | V. V. Likhvantsev V. V. Moroz O. A. Grebenchikov Yu. I., Gorokhovatsky Yu. V. Zarzhetsky S. S. Timoshin D. I. Levikov V. L. Shaibakova |
| author_sort | V. V. Likhvantsev |
| collection | DOAJ |
| description | This paper is the second part of an overview dealing with experimental and clinical studies in ischemic and pharmacological preconditioning. It considers the possibilities of practically using the available knowledge on the mechanisms of preconditioning, the interaction of agents from different groups in exhibiting the protective effects of inhaled anesthetics in anesthesiology and resuscitation. Data are given on the efficacy of the discussed processes in different organs and tissues. The possibility of using opioids and other biologically active substances that are likely to have a protective effect against hypoxia is discussed separately. The problems of remote preconditioning and post-conditioning are touched upon. The available data on the impact of choosing an anesthetic mode on the course of immediate and long-term postoperative periods and mortality rates are analyzed; the problem of the old heart is discussed. It is concluded that studies dealing with the problems of pre- and postconditioning are urgent and of great scientific and practical value. Key words: ischemic preconditioning, pharmacological preconditioning, anesthetic preconditioning, postconditioning. |
| format | Article |
| id | doaj-art-d11210a4b307437f8e4bd0fc680be4f6 |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2012-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-d11210a4b307437f8e4bd0fc680be4f62025-08-20T02:55:49ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102012-02-018110.15360/1813-9779-2012-1-61247Ischemic and Pharmacological Preconditioning (part 2)V. V. LikhvantsevV. V. MorozO. A. GrebenchikovYu. I., GorokhovatskyYu. V. ZarzhetskyS. S. TimoshinD. I. LevikovV. L. ShaibakovaThis paper is the second part of an overview dealing with experimental and clinical studies in ischemic and pharmacological preconditioning. It considers the possibilities of practically using the available knowledge on the mechanisms of preconditioning, the interaction of agents from different groups in exhibiting the protective effects of inhaled anesthetics in anesthesiology and resuscitation. Data are given on the efficacy of the discussed processes in different organs and tissues. The possibility of using opioids and other biologically active substances that are likely to have a protective effect against hypoxia is discussed separately. The problems of remote preconditioning and post-conditioning are touched upon. The available data on the impact of choosing an anesthetic mode on the course of immediate and long-term postoperative periods and mortality rates are analyzed; the problem of the old heart is discussed. It is concluded that studies dealing with the problems of pre- and postconditioning are urgent and of great scientific and practical value. Key words: ischemic preconditioning, pharmacological preconditioning, anesthetic preconditioning, postconditioning.https://www.reanimatology.com/rmt/article/view/247 |
| spellingShingle | V. V. Likhvantsev V. V. Moroz O. A. Grebenchikov Yu. I., Gorokhovatsky Yu. V. Zarzhetsky S. S. Timoshin D. I. Levikov V. L. Shaibakova Ischemic and Pharmacological Preconditioning (part 2) Общая реаниматология |
| title | Ischemic and Pharmacological Preconditioning (part 2) |
| title_full | Ischemic and Pharmacological Preconditioning (part 2) |
| title_fullStr | Ischemic and Pharmacological Preconditioning (part 2) |
| title_full_unstemmed | Ischemic and Pharmacological Preconditioning (part 2) |
| title_short | Ischemic and Pharmacological Preconditioning (part 2) |
| title_sort | ischemic and pharmacological preconditioning part 2 |
| url | https://www.reanimatology.com/rmt/article/view/247 |
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