Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty
In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstr...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2017/2120165 |
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| author | Takahisa Yamamoto Naoko Fujii Yoichi Nishimura Noboru Iwata Seiichi Nakata |
| author_facet | Takahisa Yamamoto Naoko Fujii Yoichi Nishimura Noboru Iwata Seiichi Nakata |
| author_sort | Takahisa Yamamoto |
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| description | In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient with OSAS treated using UPPP. Morphological and numerical parameter changes after surgery were compared with the corresponding preoperative values. Anatomically accurate upper airway computational models were reconstructed from computed tomographic imaging data. In addition, computed fluid dynamics analysis was performed to reveal inhalation flow characteristics before and after UPPP and clearly assess the effect of UPPP on airflow patterns in the patient’s upper airway. An important benefit of UPPP is the morphological changes in the entire upper airway, in addition to widening the restricted area. These morphological changes induce laminarization of the pharyngeal jet. To obtain sufficient efficacy of UPPP in OSAS, the morphological changes in the upper airway and the airflow pattern after the surgery must be controlled. |
| format | Article |
| id | doaj-art-d1078e779eb94289a2507a84f2bb09b3 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-d1078e779eb94289a2507a84f2bb09b32025-02-03T01:01:56ZengWileyCase Reports in Otolaryngology2090-67652090-67732017-01-01201710.1155/2017/21201652120165Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by UvulopalatopharyngoplastyTakahisa Yamamoto0Naoko Fujii1Yoichi Nishimura2Noboru Iwata3Seiichi Nakata4Department of Mechanical Engineering, National Institute of Technology, Gifu College, Motosu, JapanDepartment of Radiology, Second Hospital, Fujita Health University School of Medicine, Nagoya, JapanDepartment of Otorhinolaryngology, Second Hospital, Fujita Health University School of Medicine, Nagoya, JapanDepartment of Otorhinolaryngology, Second Hospital, Fujita Health University School of Medicine, Nagoya, JapanDepartment of Otorhinolaryngology, Second Hospital, Fujita Health University School of Medicine, Nagoya, JapanIn a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient with OSAS treated using UPPP. Morphological and numerical parameter changes after surgery were compared with the corresponding preoperative values. Anatomically accurate upper airway computational models were reconstructed from computed tomographic imaging data. In addition, computed fluid dynamics analysis was performed to reveal inhalation flow characteristics before and after UPPP and clearly assess the effect of UPPP on airflow patterns in the patient’s upper airway. An important benefit of UPPP is the morphological changes in the entire upper airway, in addition to widening the restricted area. These morphological changes induce laminarization of the pharyngeal jet. To obtain sufficient efficacy of UPPP in OSAS, the morphological changes in the upper airway and the airflow pattern after the surgery must be controlled.http://dx.doi.org/10.1155/2017/2120165 |
| spellingShingle | Takahisa Yamamoto Naoko Fujii Yoichi Nishimura Noboru Iwata Seiichi Nakata Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty Case Reports in Otolaryngology |
| title | Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty |
| title_full | Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty |
| title_fullStr | Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty |
| title_full_unstemmed | Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty |
| title_short | Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty |
| title_sort | mechanisms underlying improvement in obstructive sleep apnea syndrome by uvulopalatopharyngoplasty |
| url | http://dx.doi.org/10.1155/2017/2120165 |
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