Influence of Substrate Concentrations on the Performance of Fed-Batch and Perfusion Bioreactors: Insights from Mathematical Modelling

Influence of Substrate Concentrations on the Performance of Fed-Batch and Perfusion Bioreactors: Insights from Mathematical Modelling

Fed-batch and perfusion bioreactors are commonly used in biopharmaceutical production. This study applies mathematical models to investigate the influence of substrate concentration in the media added (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="...

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Bibliographic Details
Main Authors: John J. Fitzpatrick, Fionn O'Leary, Ali Hill, James Daly, Fergal Lalor, Edmond P. Byrne
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:ChemEngineering
Subjects:
fed-batch
perfusion
bioreactor performance
biopharmaceutical
Online Access:https://www.mdpi.com/2305-7084/9/3/48
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