From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers
With a deeper understanding of the aging process, injectable dermal fillers have revolutionized cosmetic dermatology and plastic surgery. These minimally invasive treatments address signs of aging, such as wrinkles, fine lines, and volume loss. The market for injectable dermal fillers expands yearly...
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Format: | Article |
Language: | English |
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Wiley
2025-01-01
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Series: | Advances in Polymer Technology |
Online Access: | http://dx.doi.org/10.1155/adv/3899983 |
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author | Song-Yi Wu Chen-Chi Tsai Wei-Bor Tsai |
author_facet | Song-Yi Wu Chen-Chi Tsai Wei-Bor Tsai |
author_sort | Song-Yi Wu |
collection | DOAJ |
description | With a deeper understanding of the aging process, injectable dermal fillers have revolutionized cosmetic dermatology and plastic surgery. These minimally invasive treatments address signs of aging, such as wrinkles, fine lines, and volume loss. The market for injectable dermal fillers expands yearly, with each product offering unique compositions that influence therapeutic outcomes, handling properties, and potential adverse effects. Fillers are generally classified into three major types: temporary, semi-permanent, and permanent. Temporary fillers, including hyaluronic acid (HA) and collagen (COL)-based options, provide reliable correction but typically have limited longevity. Semi-permanent and permanent fillers, made from synthetic materials like poly-L-lactic acid and polymethylmethacrylate (PMMA), offer extended durations of neocollagenesis. This review focuses specifically on COL-based fillers, discussing both FDA-approved products and those still in the research stage. |
format | Article |
id | doaj-art-d104a4a322e14497b9045324b999dd43 |
institution | Kabale University |
issn | 1098-2329 |
language | English |
publishDate | 2025-01-01 |
publisher | Wiley |
record_format | Article |
series | Advances in Polymer Technology |
spelling | doaj-art-d104a4a322e14497b9045324b999dd432025-02-08T00:00:05ZengWileyAdvances in Polymer Technology1098-23292025-01-01202510.1155/adv/3899983From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen FillersSong-Yi Wu0Chen-Chi Tsai1Wei-Bor Tsai2Department of Chemical Engineering and Program of Green Materials and Precision DevicesGuangdong Victory Biotech Co., Ltd.Department of Chemical Engineering and Program of Green Materials and Precision DevicesWith a deeper understanding of the aging process, injectable dermal fillers have revolutionized cosmetic dermatology and plastic surgery. These minimally invasive treatments address signs of aging, such as wrinkles, fine lines, and volume loss. The market for injectable dermal fillers expands yearly, with each product offering unique compositions that influence therapeutic outcomes, handling properties, and potential adverse effects. Fillers are generally classified into three major types: temporary, semi-permanent, and permanent. Temporary fillers, including hyaluronic acid (HA) and collagen (COL)-based options, provide reliable correction but typically have limited longevity. Semi-permanent and permanent fillers, made from synthetic materials like poly-L-lactic acid and polymethylmethacrylate (PMMA), offer extended durations of neocollagenesis. This review focuses specifically on COL-based fillers, discussing both FDA-approved products and those still in the research stage.http://dx.doi.org/10.1155/adv/3899983 |
spellingShingle | Song-Yi Wu Chen-Chi Tsai Wei-Bor Tsai From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers Advances in Polymer Technology |
title | From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers |
title_full | From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers |
title_fullStr | From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers |
title_full_unstemmed | From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers |
title_short | From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers |
title_sort | from bench to clinic crosslinking approaches for next generation collagen fillers |
url | http://dx.doi.org/10.1155/adv/3899983 |
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