Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation
Abstract Uveal melanoma (UM) is a rare aggressive intraocular tumour that spreads most commonly to the liver in tumours with loss of one copy of chromosome 3 (HR-M3); current treatments for metastatic disease remain largely ineffective. Pre-clinical research is increasingly using three-dimensional m...
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| Main Authors: | Karen Aughton, Joshua Hattersley, Sarah E Coupland, Helen Kalirai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-78171-2 |
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