A bespoke water T–maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice

A bespoke water T–maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice

The Morris Water Maze (MWM) is the most commonly used assay for evaluating learning and memory in laboratory mice. Despite its widespread use, contemporary reviews have highlighted substantial methodological variation in experimental protocols and that the associated testing procedures are acutely (...

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Bibliographic Details
Main Authors: Jeremy Davidson Bailoo, Susan E. Bergeson, Igor Ponomarev, Joshua O. Willms, Brent R. Kisby, Gail A. Cornwall, Clinton C. MacDonald, J. Josh Lawrence, Vadivel Ganapathy, Sathish Sivaprakasam, Praneetha Panthagani, Scott Trasti, Justin A. Varholick, Michael Findlater, Amrika Deonarine
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
refinement
Morris water maze
MWM
T-water maze
water T-maze
reproducibility
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2024.1492327/full
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