KAT7-acetylated YBX1 promotes hepatocellular carcinoma proliferation by reprogramming nucleotide metabolism

KAT7-acetylated YBX1 promotes hepatocellular carcinoma proliferation by reprogramming nucleotide metabolism

Abstract Background Lysine acetylation is a critical post-translational modification regulating tumor initiation and progression. Lysine acetyltransferase 7 (KAT7)-mediated lysine acetylation is frequently dysregulated in cancer. However, the role of KAT7-mediated lysine acetylation in hepatocellula...

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Bibliographic Details
Main Authors: He Huang, Longfei Ren, Yongqiang Zhou, Pengyu Chen, Haixia Zhao, Shang Li, Haiping Wang, Xun Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
HCC
Acetylation
KAT7
YBX1
Nucleotide metabolism
Online Access:https://doi.org/10.1186/s12885-025-13708-w
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