Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review

Background: Aloscasia macrorrhiza, commonly known as Giant Taro, is a species rich in phytochemicals with diverse pharmacological properties. Phytochemical analysis shows different bioactive compounds like alkaloids, flavonoids, terpenoids, phenolics, and saponins in different components of the plan...

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Main Authors: Amitesh Chakraborty, Santanu Giri, Aditya Dev Shah, Tushar Adhikari
Format: Article
Language:English
Published: Creative Pharma Assent 2024-12-01
Series:Journal of Applied Pharmaceutical Research
Subjects:
Online Access:https://japtronline.com/index.php/joapr/article/view/742
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author Amitesh Chakraborty
Santanu Giri
Aditya Dev Shah
Tushar Adhikari
author_facet Amitesh Chakraborty
Santanu Giri
Aditya Dev Shah
Tushar Adhikari
author_sort Amitesh Chakraborty
collection DOAJ
description Background: Aloscasia macrorrhiza, commonly known as Giant Taro, is a species rich in phytochemicals with diverse pharmacological properties. Phytochemical analysis shows different bioactive compounds like alkaloids, flavonoids, terpenoids, phenolics, and saponins in different components of the plant body, including leaves, stems, and roots. Alocasin, a class of alkaloids, is most prominent in this plant. These substances are likely responsible for different biological activities, as Aloscasia macrorrhiza shows. Aim: This review unveils the phytochemical composition and pharmacological activities of various parts of Aloscasia macrorrhiza. Method: Multiple Literature, including research and review papers, were searched for based on their title, abstracts, and keywords. Keywords like ‘Aloscasia macrorrhiza,’ ‘Phytochemistry,’ ‘Traditional uses,’ and ‘Ethnomedicinal uses’ were used to collect information. Abstracts of articles with relevant titles were screened, and the full text was considered. Only articles published from 2018 to 2024 were considered. Based on their classes and mechanistic actions, this review consolidated these phytoconstituents. Results: These phytoconstituents exhibit a wide array of therapeutic activities, including anti-inflammatory (due to tannins and polyphenols), antimicrobial (due to terpenes and lectins), antioxidant (due to polyphenols), anticancer (due to flavonoids), anti-diabetic (due to flavonoids) effects. Conclusion: This review provides insights to the therapeutic potential of Aloscasia macrorrhiza and hence forms a bridge of understanding between the traditional uses and the modern Pharmacology studies. In the future, further clarification and detailed mechanistic insight can be done. Aloscasia macrorrhiza may have potential therapeutic applications and is subject to further investigation.
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spelling doaj-art-d0d75c520eb441beb833dc139ec15a152025-08-20T02:40:10ZengCreative Pharma AssentJournal of Applied Pharmaceutical Research2348-03352024-12-01126738710.69857/joapr.v12i6.742743Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive reviewAmitesh Chakraborty0Santanu Giri1Aditya Dev Shah2Tushar Adhikari3Division of Pharmaceutical Chemistry, Department of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F, Nilgunj Rd, Sahid Colony, Panihati, Khardaha, West Bengal 700114 IndiaDivision of Pharmaceutical Chemistry, Department of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F, Nilgunj Rd, Sahid Colony, Panihati, Khardaha, West Bengal 700114 IndiaDepartment of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology; 157/F, Nilgunj Rd, Sahid Colony, Panihati, Khardaha, West Bengal 700114 IndiaDivision of Pharmaceutical Chemistry, Department of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F, Nilgunj Rd, Sahid Colony, Panihati, Khardaha, West Bengal 700114 IndiaBackground: Aloscasia macrorrhiza, commonly known as Giant Taro, is a species rich in phytochemicals with diverse pharmacological properties. Phytochemical analysis shows different bioactive compounds like alkaloids, flavonoids, terpenoids, phenolics, and saponins in different components of the plant body, including leaves, stems, and roots. Alocasin, a class of alkaloids, is most prominent in this plant. These substances are likely responsible for different biological activities, as Aloscasia macrorrhiza shows. Aim: This review unveils the phytochemical composition and pharmacological activities of various parts of Aloscasia macrorrhiza. Method: Multiple Literature, including research and review papers, were searched for based on their title, abstracts, and keywords. Keywords like ‘Aloscasia macrorrhiza,’ ‘Phytochemistry,’ ‘Traditional uses,’ and ‘Ethnomedicinal uses’ were used to collect information. Abstracts of articles with relevant titles were screened, and the full text was considered. Only articles published from 2018 to 2024 were considered. Based on their classes and mechanistic actions, this review consolidated these phytoconstituents. Results: These phytoconstituents exhibit a wide array of therapeutic activities, including anti-inflammatory (due to tannins and polyphenols), antimicrobial (due to terpenes and lectins), antioxidant (due to polyphenols), anticancer (due to flavonoids), anti-diabetic (due to flavonoids) effects. Conclusion: This review provides insights to the therapeutic potential of Aloscasia macrorrhiza and hence forms a bridge of understanding between the traditional uses and the modern Pharmacology studies. In the future, further clarification and detailed mechanistic insight can be done. Aloscasia macrorrhiza may have potential therapeutic applications and is subject to further investigation.https://japtronline.com/index.php/joapr/article/view/742aloscasia macrorrhizagiant taroanticancerantioxidant
spellingShingle Amitesh Chakraborty
Santanu Giri
Aditya Dev Shah
Tushar Adhikari
Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
Journal of Applied Pharmaceutical Research
aloscasia macrorrhiza
giant taro
anticancer
antioxidant
title Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
title_full Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
title_fullStr Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
title_full_unstemmed Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
title_short Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
title_sort phytochemistry and pharmacological potential of aloscasia macrorrhiza a comprehensive review
topic aloscasia macrorrhiza
giant taro
anticancer
antioxidant
url https://japtronline.com/index.php/joapr/article/view/742
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AT tusharadhikari phytochemistryandpharmacologicalpotentialofaloscasiamacrorrhizaacomprehensivereview