Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis
Introduction: Malignant gastrointestinal neuroectodermal tumor (GNET), previously known as clear cell sarcoma-like tumor of the gastrointestinal tract, is an extremely rare and aggressive mesenchymal neoplasm characterized by high rates of recurrence, metastases, and mortality. Currently,...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2024-12-01
|
| Series: | Case Reports in Gastroenterology |
| Online Access: | https://karger.com/article/doi/10.1159/000542659 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849727636344930304 |
|---|---|
| author | Tianyu She Stephanie Ren Seymour Katz |
| author_facet | Tianyu She Stephanie Ren Seymour Katz |
| author_sort | Tianyu She |
| collection | DOAJ |
| description |
Introduction: Malignant gastrointestinal neuroectodermal tumor (GNET), previously known as clear cell sarcoma-like tumor of the gastrointestinal tract, is an extremely rare and aggressive mesenchymal neoplasm characterized by high rates of recurrence, metastases, and mortality. Currently, there are no standardized guidelines for therapy. Case Presentation: We present a case of GNET in a 32-year-old male with a history of lymphoma and ulcerative colitis (UC), who also had synchronous multiple liver metastasis. To our knowledge, this is the first documented case of GNET in a patient with inflammatory bowel disease. Conclusion: The narrow time frame in which UC and GNET were diagnosed warrants further investigation into their potential relationship. |
| format | Article |
| id | doaj-art-d0bf18055da546ada5db346de38e4dcc |
| institution | DOAJ |
| issn | 1662-0631 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj-art-d0bf18055da546ada5db346de38e4dcc2025-08-20T03:09:47ZengKarger PublishersCase Reports in Gastroenterology1662-06312024-12-0118144945310.1159/000542659Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative ColitisTianyu SheStephanie RenSeymour Katz Introduction: Malignant gastrointestinal neuroectodermal tumor (GNET), previously known as clear cell sarcoma-like tumor of the gastrointestinal tract, is an extremely rare and aggressive mesenchymal neoplasm characterized by high rates of recurrence, metastases, and mortality. Currently, there are no standardized guidelines for therapy. Case Presentation: We present a case of GNET in a 32-year-old male with a history of lymphoma and ulcerative colitis (UC), who also had synchronous multiple liver metastasis. To our knowledge, this is the first documented case of GNET in a patient with inflammatory bowel disease. Conclusion: The narrow time frame in which UC and GNET were diagnosed warrants further investigation into their potential relationship. https://karger.com/article/doi/10.1159/000542659 |
| spellingShingle | Tianyu She Stephanie Ren Seymour Katz Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis Case Reports in Gastroenterology |
| title | Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis |
| title_full | Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis |
| title_fullStr | Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis |
| title_full_unstemmed | Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis |
| title_short | Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis |
| title_sort | gastrointestinal neuroectodermal tumor extraskeletal ewing sarcoma of the ileum with ulcerative colitis |
| url | https://karger.com/article/doi/10.1159/000542659 |
| work_keys_str_mv | AT tianyushe gastrointestinalneuroectodermaltumorextraskeletalewingsarcomaoftheileumwithulcerativecolitis AT stephanieren gastrointestinalneuroectodermaltumorextraskeletalewingsarcomaoftheileumwithulcerativecolitis AT seymourkatz gastrointestinalneuroectodermaltumorextraskeletalewingsarcomaoftheileumwithulcerativecolitis |