Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits

Early detection of any disease is always a life-saving methodology for human beings likewise the detection of p24 antigen is always better than the detection of HIV antibodies. In the current era, p24 antigen is added additionally in HIV antibodies detection assays and called HIV fourth-generation i...

Full description

Saved in:
Bibliographic Details
Main Authors: Rajesh Kumar Sharma, Bharti Chauhan, Ashrat Manzoor, Rajeev Kumar, Daud Ali, Rich Baranwal, Akanksha Bisht, Harish Chander, Anup Anvikar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:https://journals.lww.com/10.4103/ajts.ajts_224_23
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850080904742961152
author Rajesh Kumar Sharma
Bharti Chauhan
Ashrat Manzoor
Rajeev Kumar
Daud Ali
Rich Baranwal
Akanksha Bisht
Harish Chander
Anup Anvikar
author_facet Rajesh Kumar Sharma
Bharti Chauhan
Ashrat Manzoor
Rajeev Kumar
Daud Ali
Rich Baranwal
Akanksha Bisht
Harish Chander
Anup Anvikar
author_sort Rajesh Kumar Sharma
collection DOAJ
description Early detection of any disease is always a life-saving methodology for human beings likewise the detection of p24 antigen is always better than the detection of HIV antibodies. In the current era, p24 antigen is added additionally in HIV antibodies detection assays and called HIV fourth-generation immunodiagnostic kit. The different HIV fourth-generation kit having different capacities to pick up the low concentration of analyte as well as represent the detection values in different units. A total of 30 assays were used in this study and it was found that the detection concentration assigned by the manufacturers in the case of imported kits was 0.48 IU/mL to 2 IU/mL. However, the detection range of the indigenous kits was 25 pg/mL to 1000 IU/mL. This study gives an idea/knowledge for the startups concerned with high hope and broad scope for make in India concept in the IVDs market.
format Article
id doaj-art-d0bd732fe4a84407b5044ecb0dce28b1
institution DOAJ
issn 0973-6247
1998-3565
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Journal of Transfusion Science
spelling doaj-art-d0bd732fe4a84407b5044ecb0dce28b12025-08-20T02:44:50ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-12-0118235936210.4103/ajts.ajts_224_23Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kitsRajesh Kumar SharmaBharti ChauhanAshrat ManzoorRajeev KumarDaud AliRich BaranwalAkanksha BishtHarish ChanderAnup AnvikarEarly detection of any disease is always a life-saving methodology for human beings likewise the detection of p24 antigen is always better than the detection of HIV antibodies. In the current era, p24 antigen is added additionally in HIV antibodies detection assays and called HIV fourth-generation immunodiagnostic kit. The different HIV fourth-generation kit having different capacities to pick up the low concentration of analyte as well as represent the detection values in different units. A total of 30 assays were used in this study and it was found that the detection concentration assigned by the manufacturers in the case of imported kits was 0.48 IU/mL to 2 IU/mL. However, the detection range of the indigenous kits was 25 pg/mL to 1000 IU/mL. This study gives an idea/knowledge for the startups concerned with high hope and broad scope for make in India concept in the IVDs market.https://journals.lww.com/10.4103/ajts.ajts_224_23detection concentrationhivp24 antigen
spellingShingle Rajesh Kumar Sharma
Bharti Chauhan
Ashrat Manzoor
Rajeev Kumar
Daud Ali
Rich Baranwal
Akanksha Bisht
Harish Chander
Anup Anvikar
Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
Asian Journal of Transfusion Science
detection concentration
hiv
p24 antigen
title Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
title_full Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
title_fullStr Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
title_full_unstemmed Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
title_short Comparison: Imported and Indigenous HIV Fourth-generation immunodiagnostic kits
title_sort comparison imported and indigenous hiv fourth generation immunodiagnostic kits
topic detection concentration
hiv
p24 antigen
url https://journals.lww.com/10.4103/ajts.ajts_224_23
work_keys_str_mv AT rajeshkumarsharma comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT bhartichauhan comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT ashratmanzoor comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT rajeevkumar comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT daudali comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT richbaranwal comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT akankshabisht comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT harishchander comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits
AT anupanvikar comparisonimportedandindigenoushivfourthgenerationimmunodiagnostickits