Modern potentials of prokinetics in treatment of gastroesophageal reflux disease

The aim of review. To estimate up-to-date options and prospects of application of prokinetics in treatment of gastroesophageal reflux disease (GERD).Original positions. Nowadays proton pump inhibitors (PPI) are the basic drugs used in treatment of GERD. At the same time in last years cases of their...

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Main Authors: A. A. Sheptulin, V. A. Kiprianis
Format: Article
Language:Russian
Published: Gastro LLC 2010-11-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/1566
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author A. A. Sheptulin
V. A. Kiprianis
author_facet A. A. Sheptulin
V. A. Kiprianis
author_sort A. A. Sheptulin
collection DOAJ
description The aim of review. To estimate up-to-date options and prospects of application of prokinetics in treatment of gastroesophageal reflux disease (GERD).Original positions. Nowadays proton pump inhibitors (PPI) are the basic drugs used in treatment of GERD. At the same time in last years cases of their inefficacy became frequent that can be caused by «night acid outbreak», and also non-acid refluxes. As GERD is diseases with primary disorders of motility of the esophagus and the stomach, in its treatment prokinetics (domperidone, itopride hydrochloride) can be applied.Conclusion. In the case of resistance of GERD prokinetics can be added to PPI treatment (itopride hydrochloride, domperidone).
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publishDate 2010-11-01
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-d0b88725c0ca4917bb0a2699179815692025-02-10T16:14:30ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732010-11-0120539431070Modern potentials of prokinetics in treatment of gastroesophageal reflux diseaseA. A. SheptulinV. A. KiprianisThe aim of review. To estimate up-to-date options and prospects of application of prokinetics in treatment of gastroesophageal reflux disease (GERD).Original positions. Nowadays proton pump inhibitors (PPI) are the basic drugs used in treatment of GERD. At the same time in last years cases of their inefficacy became frequent that can be caused by «night acid outbreak», and also non-acid refluxes. As GERD is diseases with primary disorders of motility of the esophagus and the stomach, in its treatment prokinetics (domperidone, itopride hydrochloride) can be applied.Conclusion. In the case of resistance of GERD prokinetics can be added to PPI treatment (itopride hydrochloride, domperidone).https://www.gastro-j.ru/jour/article/view/1566gastroesophageal reflux diseaseprokinetics
spellingShingle A. A. Sheptulin
V. A. Kiprianis
Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
gastroesophageal reflux disease
prokinetics
title Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
title_full Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
title_fullStr Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
title_full_unstemmed Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
title_short Modern potentials of prokinetics in treatment of gastroesophageal reflux disease
title_sort modern potentials of prokinetics in treatment of gastroesophageal reflux disease
topic gastroesophageal reflux disease
prokinetics
url https://www.gastro-j.ru/jour/article/view/1566
work_keys_str_mv AT aasheptulin modernpotentialsofprokineticsintreatmentofgastroesophagealrefluxdisease
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