State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications
The aim of this review is to investigate the possibility of fabricating coatings functionalized with bioactive molecules. These coatings are interesting when applied to biomedical devices, particularly in the orthopedic field. In fact, the application of calcium phosphate-based coatings on the surfa...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-08-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/15/15/1199 |
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| author | Matteo Montesissa Viviana Tommasini Katia Rubini Marco Boi Nicola Baldini Elisa Boanini |
| author_facet | Matteo Montesissa Viviana Tommasini Katia Rubini Marco Boi Nicola Baldini Elisa Boanini |
| author_sort | Matteo Montesissa |
| collection | DOAJ |
| description | The aim of this review is to investigate the possibility of fabricating coatings functionalized with bioactive molecules. These coatings are interesting when applied to biomedical devices, particularly in the orthopedic field. In fact, the application of calcium phosphate-based coatings on the surface of implanted devices is an effective strategy to increase their osteoinductive and osseointegrative properties. Several coating fabrication technologies are presented, including chemical deposition and physical methods. The application of bioactive molecules in combination with calcium phosphate coatings may improve their osteointegrative, antibacterial, and antitumor properties, therefore increasing the performance of implantable devices. |
| format | Article |
| id | doaj-art-d0b2e5ede6b147c3a6364652b2357502 |
| institution | Kabale University |
| issn | 2079-4991 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-d0b2e5ede6b147c3a6364652b23575022025-08-20T03:36:22ZengMDPI AGNanomaterials2079-49912025-08-011515119910.3390/nano15151199State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic ApplicationsMatteo Montesissa0Viviana Tommasini1Katia Rubini2Marco Boi3Nicola Baldini4Elisa Boanini5Biomedical Science and Technologies and NanoBiotechnologies Lab, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyBiomedical Science and Technologies and NanoBiotechnologies Lab, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Chemistry “Giacomo Ciamician”, University of Bologna, 40129 Bologna, ItalyBiomedical Science and Technologies and NanoBiotechnologies Lab, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyBiomedical Science and Technologies and NanoBiotechnologies Lab, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Chemistry “Giacomo Ciamician”, University of Bologna, 40129 Bologna, ItalyThe aim of this review is to investigate the possibility of fabricating coatings functionalized with bioactive molecules. These coatings are interesting when applied to biomedical devices, particularly in the orthopedic field. In fact, the application of calcium phosphate-based coatings on the surface of implanted devices is an effective strategy to increase their osteoinductive and osseointegrative properties. Several coating fabrication technologies are presented, including chemical deposition and physical methods. The application of bioactive molecules in combination with calcium phosphate coatings may improve their osteointegrative, antibacterial, and antitumor properties, therefore increasing the performance of implantable devices.https://www.mdpi.com/2079-4991/15/15/1199coatingdeposition techniquesorthopedic surgeryantibacterial effectantitumoral effectpro-osseointegration effect |
| spellingShingle | Matteo Montesissa Viviana Tommasini Katia Rubini Marco Boi Nicola Baldini Elisa Boanini State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications Nanomaterials coating deposition techniques orthopedic surgery antibacterial effect antitumoral effect pro-osseointegration effect |
| title | State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications |
| title_full | State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications |
| title_fullStr | State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications |
| title_full_unstemmed | State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications |
| title_short | State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications |
| title_sort | state of art and perspective of calcium phosphate based coatings coupled with bioactive compounds for orthopedic applications |
| topic | coating deposition techniques orthopedic surgery antibacterial effect antitumoral effect pro-osseointegration effect |
| url | https://www.mdpi.com/2079-4991/15/15/1199 |
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