A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles

Background and Aims. There are limited data on the differences in diagnostic yield between 25-gauge and 22-gauge EUS-FNA needles. This prospective study compared the difference in diagnostic yield between a 22-gauge and a 25-gauge needle when performing EUS-FNA. Methods. Forty-three patients with...

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Main Authors: Hiroo Imazu, Yujiro Uchiyama, Hiroshi Kakutani, kei-ichi Ikeda, Kazuki Sumiyama, Mitsuru Kaise, Salem Omar, Tiing Leong Ang, Hisao Tajiri
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2009/546390
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author Hiroo Imazu
Yujiro Uchiyama
Hiroshi Kakutani
kei-ichi Ikeda
Kazuki Sumiyama
Mitsuru Kaise
Salem Omar
Tiing Leong Ang
Hisao Tajiri
author_facet Hiroo Imazu
Yujiro Uchiyama
Hiroshi Kakutani
kei-ichi Ikeda
Kazuki Sumiyama
Mitsuru Kaise
Salem Omar
Tiing Leong Ang
Hisao Tajiri
author_sort Hiroo Imazu
collection DOAJ
description Background and Aims. There are limited data on the differences in diagnostic yield between 25-gauge and 22-gauge EUS-FNA needles. This prospective study compared the difference in diagnostic yield between a 22-gauge and a 25-gauge needle when performing EUS-FNA. Methods. Forty-three patients with intraluminal or extraluminal mass lesions and/or lymphadenopathy were enrolled prospectively. EUS-FNA was performed for each mass lesion using both 25- and 22-gauge needles. The differences in accuracy rate, scoring of needle visibility, ease of puncture and quantity of obtained specimen were evaluated. Results. The overall accuracy of 22- and 25-gauge needle was similar at 81% and 76% respectively (N.S). Likewise the visibility scores of both needles were also similar. Overall the quantity of specimen obtained higher with the 22-gauge needle (score: 1.64 vs. P<.001). However the 25-gauge needle was significantly superior to the 22-gauge needle in terms of ease of puncture (score: 1.9 vs. 1.29, P<.001) and in the quantity of specimen in the context of pancreatic mass EUS-FNA (score: 1.8 vs. 1.58, P<.05). Conclusion. The 22-gauge and 25-gauge needles have similar overall diagnostic yield. The 25-gauge needle appeared superior in the subset of patients with hard lesions and pancreatic masses.
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spelling doaj-art-d0b0034ced71450c8abd2a72957593b12025-08-20T02:20:02ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/546390546390A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge NeedlesHiroo Imazu0Yujiro Uchiyama1Hiroshi Kakutani2kei-ichi Ikeda3Kazuki Sumiyama4Mitsuru Kaise5Salem Omar6Tiing Leong Ang7Hisao Tajiri8Department of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDivision of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, MalaysiaDivision of Gastroenterology, Department of Medicine, Changi General Hospital, 529889, SingaporeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University, Tokyo 105-8461, JapanBackground and Aims. There are limited data on the differences in diagnostic yield between 25-gauge and 22-gauge EUS-FNA needles. This prospective study compared the difference in diagnostic yield between a 22-gauge and a 25-gauge needle when performing EUS-FNA. Methods. Forty-three patients with intraluminal or extraluminal mass lesions and/or lymphadenopathy were enrolled prospectively. EUS-FNA was performed for each mass lesion using both 25- and 22-gauge needles. The differences in accuracy rate, scoring of needle visibility, ease of puncture and quantity of obtained specimen were evaluated. Results. The overall accuracy of 22- and 25-gauge needle was similar at 81% and 76% respectively (N.S). Likewise the visibility scores of both needles were also similar. Overall the quantity of specimen obtained higher with the 22-gauge needle (score: 1.64 vs. P<.001). However the 25-gauge needle was significantly superior to the 22-gauge needle in terms of ease of puncture (score: 1.9 vs. 1.29, P<.001) and in the quantity of specimen in the context of pancreatic mass EUS-FNA (score: 1.8 vs. 1.58, P<.05). Conclusion. The 22-gauge and 25-gauge needles have similar overall diagnostic yield. The 25-gauge needle appeared superior in the subset of patients with hard lesions and pancreatic masses.http://dx.doi.org/10.1155/2009/546390
spellingShingle Hiroo Imazu
Yujiro Uchiyama
Hiroshi Kakutani
kei-ichi Ikeda
Kazuki Sumiyama
Mitsuru Kaise
Salem Omar
Tiing Leong Ang
Hisao Tajiri
A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
Gastroenterology Research and Practice
title A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
title_full A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
title_fullStr A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
title_full_unstemmed A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
title_short A Prospective Comparison of EUS-Guided FNA Using 25-Gauge and 22-Gauge Needles
title_sort prospective comparison of eus guided fna using 25 gauge and 22 gauge needles
url http://dx.doi.org/10.1155/2009/546390
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