Emerging role of N-acetyltransferase 10 in diseases: RNA ac4C modification and beyond

Emerging role of N-acetyltransferase 10 in diseases: RNA ac4C modification and beyond

Abstract N4-acetylcytidine (ac4C), a conserved RNA modification, plays critical roles in RNA stability and translation. As the primary enzyme catalyzing ac4C, N-acetyltransferase 10 (NAT10) is increasingly implicated in diverse diseases. This review systematically explores NAT10’s multifaceted contr...

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Bibliographic Details
Main Authors: Lin Jiao, Yanjun Si, Yushan Yuan, Xinxing Lei, Qian Jiang, Lijun Yang, Wenhao Mao, Binwu Ying, Liwei Ma, Ting Sun
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Molecular Biomedicine
Subjects:
N-acetyltransferase 10
RNA modification
N4-acetylcytidine
Cancer
Disease
Online Access:https://doi.org/10.1186/s43556-025-00286-3
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