A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study
Abstract Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. Previous research has highlighted a potential link between PCOS and Müllerian anomalies. The present cross-sectional study aimed to evaluate the prevalence of polycystic ovary morphology (...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-91531-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849768041719529472 |
|---|---|
| author | Shohreh Irani Atiyeh Najafi Samira Vesali Mehri Mashayekhi Fatemeh Niknejad Firoozeh Ahmadi |
| author_facet | Shohreh Irani Atiyeh Najafi Samira Vesali Mehri Mashayekhi Fatemeh Niknejad Firoozeh Ahmadi |
| author_sort | Shohreh Irani |
| collection | DOAJ |
| description | Abstract Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. Previous research has highlighted a potential link between PCOS and Müllerian anomalies. The present cross-sectional study aimed to evaluate the prevalence of polycystic ovary morphology (PCOM) in infertile patients with uterine anomalies (septate and arcuate uterine), attending the Royan Research Institute in Tehran, Iran, between January 2021 and December 2022. A total of 884 infertile women who underwent 3D-hysterosonography at the Institute were included in the study. The participants were divided into two groups: 127 women with uterine anomalies and 757 women without. Data was collected from the participants’ medical records. The results showed that the frequency of PCOM was significantly higher in women with uterine anomalies (40.9%, 52 women) compared to those without such anomalies (14.7%, 111 women) (p = 0.0001). A higher prevalence of PCOM in women with uterine anomalies highlights the need for targeted screening within this population and underscores the importance of integrated diagnostic approaches. |
| format | Article |
| id | doaj-art-d0a12449560a4dd7a9567b4bf7a8ceb9 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-d0a12449560a4dd7a9567b4bf7a8ceb92025-08-20T03:03:58ZengNature PortfolioScientific Reports2045-23222025-02-011511610.1038/s41598-025-91531-wA survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional studyShohreh Irani0Atiyeh Najafi1Samira Vesali2Mehri Mashayekhi3Fatemeh Niknejad4Firoozeh Ahmadi5Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECRDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECRReproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECRDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECRDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECRDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECRAbstract Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. Previous research has highlighted a potential link between PCOS and Müllerian anomalies. The present cross-sectional study aimed to evaluate the prevalence of polycystic ovary morphology (PCOM) in infertile patients with uterine anomalies (septate and arcuate uterine), attending the Royan Research Institute in Tehran, Iran, between January 2021 and December 2022. A total of 884 infertile women who underwent 3D-hysterosonography at the Institute were included in the study. The participants were divided into two groups: 127 women with uterine anomalies and 757 women without. Data was collected from the participants’ medical records. The results showed that the frequency of PCOM was significantly higher in women with uterine anomalies (40.9%, 52 women) compared to those without such anomalies (14.7%, 111 women) (p = 0.0001). A higher prevalence of PCOM in women with uterine anomalies highlights the need for targeted screening within this population and underscores the importance of integrated diagnostic approaches.https://doi.org/10.1038/s41598-025-91531-wUterine abnormalitiesPolycystic ovary morphology (PCOM)Septate uterineArcuate uterinePolycystic ovarian syndrome (PCOS) |
| spellingShingle | Shohreh Irani Atiyeh Najafi Samira Vesali Mehri Mashayekhi Fatemeh Niknejad Firoozeh Ahmadi A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study Scientific Reports Uterine abnormalities Polycystic ovary morphology (PCOM) Septate uterine Arcuate uterine Polycystic ovarian syndrome (PCOS) |
| title | A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study |
| title_full | A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study |
| title_fullStr | A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study |
| title_full_unstemmed | A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study |
| title_short | A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study |
| title_sort | survey on the frequency of polycystic ovary morphology pcom in infertile patients with septate and arcuate uterine anomalies a cross sectional study |
| topic | Uterine abnormalities Polycystic ovary morphology (PCOM) Septate uterine Arcuate uterine Polycystic ovarian syndrome (PCOS) |
| url | https://doi.org/10.1038/s41598-025-91531-w |
| work_keys_str_mv | AT shohrehirani asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT atiyehnajafi asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT samiravesali asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT mehrimashayekhi asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT fatemehniknejad asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT firoozehahmadi asurveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT shohrehirani surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT atiyehnajafi surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT samiravesali surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT mehrimashayekhi surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT fatemehniknejad surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy AT firoozehahmadi surveyonthefrequencyofpolycysticovarymorphologypcomininfertilepatientswithseptateandarcuateuterineanomaliesacrosssectionalstudy |