Review: Helicobacter pylori and extragastric diseases

Infection with H. pylori causes chronic gastritis and is the most important risk factor for gastric cancer. Besides gastric disease, infection is also thought to play a role in the development of other human diseases. H. pylori has been predominantly associated with gastrointestinal, metabolic, card...

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Main Authors: J. Wizenty, M. Sigal
Format: Article
Language:English
Published: Verduci Editore 2024-09-01
Series:Microbiota in Health and Disease
Subjects:
Online Access:https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1048.pdf
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author J. Wizenty
M. Sigal
author_facet J. Wizenty
M. Sigal
author_sort J. Wizenty
collection DOAJ
description Infection with H. pylori causes chronic gastritis and is the most important risk factor for gastric cancer. Besides gastric disease, infection is also thought to play a role in the development of other human diseases. H. pylori has been predominantly associated with gastrointestinal, metabolic, cardiovascular, respiratory, and neurological disorders. In the past year, novel evidence has demonstrated a significant impact on human morbidity and mortality, mostly derived from association studies. In addition, novel experimental data have revealed direct and indirect mechanisms through which H. pylori affects extragastric organs. This article provides an update on the current knowledge of extragastric diseases associated with H. pylori infection.
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series Microbiota in Health and Disease
spelling doaj-art-d09f4fb98ad2419a930badbd8814f9982025-01-03T10:30:12ZengVerduci EditoreMicrobiota in Health and Disease2704-88452024-09-01610.26355/mhd_20249_10481048Review: Helicobacter pylori and extragastric diseasesJ. Wizenty0M. Sigal1Department of Hepatology and Gastroenterology, Charité – Universitätsmedizin Berlin, Berlin, GermanyDepartment of Hepatology and Gastroenterology, Charité – Universitätsmedizin Berlin, Berlin, GermanyInfection with H. pylori causes chronic gastritis and is the most important risk factor for gastric cancer. Besides gastric disease, infection is also thought to play a role in the development of other human diseases. H. pylori has been predominantly associated with gastrointestinal, metabolic, cardiovascular, respiratory, and neurological disorders. In the past year, novel evidence has demonstrated a significant impact on human morbidity and mortality, mostly derived from association studies. In addition, novel experimental data have revealed direct and indirect mechanisms through which H. pylori affects extragastric organs. This article provides an update on the current knowledge of extragastric diseases associated with H. pylori infection.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1048.pdfh. pylorigastrointestinal diseasemetabolic disordercardiovascular diseaserespiratory diseaseneurological disorders.
spellingShingle J. Wizenty
M. Sigal
Review: Helicobacter pylori and extragastric diseases
Microbiota in Health and Disease
h. pylori
gastrointestinal disease
metabolic disorder
cardiovascular disease
respiratory disease
neurological disorders.
title Review: Helicobacter pylori and extragastric diseases
title_full Review: Helicobacter pylori and extragastric diseases
title_fullStr Review: Helicobacter pylori and extragastric diseases
title_full_unstemmed Review: Helicobacter pylori and extragastric diseases
title_short Review: Helicobacter pylori and extragastric diseases
title_sort review helicobacter pylori and extragastric diseases
topic h. pylori
gastrointestinal disease
metabolic disorder
cardiovascular disease
respiratory disease
neurological disorders.
url https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1048.pdf
work_keys_str_mv AT jwizenty reviewhelicobacterpyloriandextragastricdiseases
AT msigal reviewhelicobacterpyloriandextragastricdiseases