MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata

The bHLH transcription factor is known to regulate cold signals and stress tolerance. In the present study, a new bHLH gene MbbHLH93, located in the nucleus, was isolated from Malus baccata, whose up-regulated expression were strongly induced by cold and drought treatment, and MbbHLH93-overexpressed...

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Main Authors: Lihua Zhang, Yu Xu, Long Lv, Tianhe Wang, Wanda Liu, Xingguo Li, Wenhui Li, Junwei Huo, Deguo Han
Format: Article
Language:English
Published: Maximum Academic Press 2024-01-01
Series:Fruit Research
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Online Access:https://www.maxapress.com/article/doi/10.48130/frures-0024-0032
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author Lihua Zhang
Yu Xu
Long Lv
Tianhe Wang
Wanda Liu
Xingguo Li
Wenhui Li
Junwei Huo
Deguo Han
author_facet Lihua Zhang
Yu Xu
Long Lv
Tianhe Wang
Wanda Liu
Xingguo Li
Wenhui Li
Junwei Huo
Deguo Han
author_sort Lihua Zhang
collection DOAJ
description The bHLH transcription factor is known to regulate cold signals and stress tolerance. In the present study, a new bHLH gene MbbHLH93, located in the nucleus, was isolated from Malus baccata, whose up-regulated expression were strongly induced by cold and drought treatment, and MbbHLH93-overexpressed heterologous lettuce plants displayed cold and drought stress-tolerant phenotypes. Determination of physiological and biochemical indexes associated with abiotic stress responses showed that overexpression of MbbHLH93 increased the activities of antioxidant enzymes superoxide dismutase, peroxidase, and catalase in lettuce plants treated with cold and drought stress, and decreased the contents of H2O2, O2·−, and malondialdehyde, which contributed to reducing cell membrane lipid peroxidation. Meanwhile, the accumulation of proline in transgenic plant cells increased, regulating cell osmotic pressure. Furthermore, quantitative expression analysis indicated that overexpression of MbbHLH93 improved the expression levels of LsCBFs, which were positive functional genes in response to cold and drought stress, enhancing plant tolerance. This research demonstrates that the MbbHLH93 is a key regulator in plant tolerance to cold and drought stresses, providing new knowledge for plant tolerance regulation.
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spelling doaj-art-d097fde1e0e2469f85bedd9a863fc49a2025-08-20T02:27:11ZengMaximum Academic PressFruit Research2769-46152024-01-014111110.48130/frures-0024-0032frures-0024-0032MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccataLihua Zhang0Yu Xu1Long Lv2Tianhe Wang3Wanda Liu4Xingguo Li5Wenhui Li6Junwei Huo7Deguo Han8The Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaHorticulture Branch of Heilongjiang Academy of Agricultural Sciences, Harbin 150040, Heilongjiang, ChinaHorticulture Branch of Heilongjiang Academy of Agricultural Sciences, Harbin 150040, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions, College of Horticulture & Landscape Architecture, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaThe bHLH transcription factor is known to regulate cold signals and stress tolerance. In the present study, a new bHLH gene MbbHLH93, located in the nucleus, was isolated from Malus baccata, whose up-regulated expression were strongly induced by cold and drought treatment, and MbbHLH93-overexpressed heterologous lettuce plants displayed cold and drought stress-tolerant phenotypes. Determination of physiological and biochemical indexes associated with abiotic stress responses showed that overexpression of MbbHLH93 increased the activities of antioxidant enzymes superoxide dismutase, peroxidase, and catalase in lettuce plants treated with cold and drought stress, and decreased the contents of H2O2, O2·−, and malondialdehyde, which contributed to reducing cell membrane lipid peroxidation. Meanwhile, the accumulation of proline in transgenic plant cells increased, regulating cell osmotic pressure. Furthermore, quantitative expression analysis indicated that overexpression of MbbHLH93 improved the expression levels of LsCBFs, which were positive functional genes in response to cold and drought stress, enhancing plant tolerance. This research demonstrates that the MbbHLH93 is a key regulator in plant tolerance to cold and drought stresses, providing new knowledge for plant tolerance regulation.https://www.maxapress.com/article/doi/10.48130/frures-0024-0032malus baccatambbhlh93cold and drought stresstranscriptional regulation
spellingShingle Lihua Zhang
Yu Xu
Long Lv
Tianhe Wang
Wanda Liu
Xingguo Li
Wenhui Li
Junwei Huo
Deguo Han
MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
Fruit Research
malus baccata
mbbhlh93
cold and drought stress
transcriptional regulation
title MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
title_full MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
title_fullStr MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
title_full_unstemmed MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
title_short MbbHLH93, a transcription factor associated with cold and drought tolerance in Malus baccata
title_sort mbbhlh93 a transcription factor associated with cold and drought tolerance in malus baccata
topic malus baccata
mbbhlh93
cold and drought stress
transcriptional regulation
url https://www.maxapress.com/article/doi/10.48130/frures-0024-0032
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