Correction of Hypothyroidism Seems to Have No Effect on Body Fat
Aim. We aimed to observe the effects of L-thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism. Methods. Forty-two women with naive autoimmune hypothyroidism were included. Also,...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/576794 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552049665900544 |
|---|---|
| author | Okan Bakiner Emre Bozkirli Emine Duygu Ersozlu Bozkirli Kursat Ozsahin |
| author_facet | Okan Bakiner Emre Bozkirli Emine Duygu Ersozlu Bozkirli Kursat Ozsahin |
| author_sort | Okan Bakiner |
| collection | DOAJ |
| description | Aim. We aimed to observe the effects of L-thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism. Methods. Forty-two women with naive autoimmune hypothyroidism were included. Also, 40 healthy participants were enrolled as a control group. Weight, body mass index, waist circumference, and subscapulary, suprailiac, femur, biceps, and triceps skin fold thicknesses were measured. Body fat percentages were calculated and body fat measurements were performed. Euthyroidism was maintained with L-thyroxine. At the 6th and 18th month, of therapy, measurements were reperformed. Results. Mean TSH levels were mIU/L in hypothyroid group and mIU/L in control subjects at admission. In hypothyroid patients, calculated body fat percentages were greater than those of the control subjects during follow-up. Body fat percentage of each hypothyroid case decreased at 6- and 18-month controls, but the decrements were statistically insignificant. Although skin fold thicknesses measured from all sites were observed to decline, only those obtained from femur and biceps showed a significant decrease ( and , resp.). Discussion. Correction of hypothyroidism did not cause any improvement in body weight and body fat percentage. The decrease in skin fold thicknesses might probably result from the reduction in subcutaneous mucopolysaccharide deposits. |
| format | Article |
| id | doaj-art-d09710b9baae47b5b21bcb2d1119f84d |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-d09710b9baae47b5b21bcb2d1119f84d2025-02-03T05:59:49ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/576794576794Correction of Hypothyroidism Seems to Have No Effect on Body FatOkan Bakiner0Emre Bozkirli1Emine Duygu Ersozlu Bozkirli2Kursat Ozsahin3Department of Endocrinology and Metabolism Diseases, School of Medicine, Başkent University, 01250 Adana, TurkeyDepartment of Endocrinology and Metabolism Diseases, School of Medicine, Başkent University, 01250 Adana, TurkeyDepartment of Internal Medicine, School of Medicine, Başkent University, 01250 Adana, TurkeyDepartment of Family Medicine, School of Medicine, Başkent University, 01250 Adana, TurkeyAim. We aimed to observe the effects of L-thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism. Methods. Forty-two women with naive autoimmune hypothyroidism were included. Also, 40 healthy participants were enrolled as a control group. Weight, body mass index, waist circumference, and subscapulary, suprailiac, femur, biceps, and triceps skin fold thicknesses were measured. Body fat percentages were calculated and body fat measurements were performed. Euthyroidism was maintained with L-thyroxine. At the 6th and 18th month, of therapy, measurements were reperformed. Results. Mean TSH levels were mIU/L in hypothyroid group and mIU/L in control subjects at admission. In hypothyroid patients, calculated body fat percentages were greater than those of the control subjects during follow-up. Body fat percentage of each hypothyroid case decreased at 6- and 18-month controls, but the decrements were statistically insignificant. Although skin fold thicknesses measured from all sites were observed to decline, only those obtained from femur and biceps showed a significant decrease ( and , resp.). Discussion. Correction of hypothyroidism did not cause any improvement in body weight and body fat percentage. The decrease in skin fold thicknesses might probably result from the reduction in subcutaneous mucopolysaccharide deposits.http://dx.doi.org/10.1155/2013/576794 |
| spellingShingle | Okan Bakiner Emre Bozkirli Emine Duygu Ersozlu Bozkirli Kursat Ozsahin Correction of Hypothyroidism Seems to Have No Effect on Body Fat International Journal of Endocrinology |
| title | Correction of Hypothyroidism Seems to Have No Effect on Body Fat |
| title_full | Correction of Hypothyroidism Seems to Have No Effect on Body Fat |
| title_fullStr | Correction of Hypothyroidism Seems to Have No Effect on Body Fat |
| title_full_unstemmed | Correction of Hypothyroidism Seems to Have No Effect on Body Fat |
| title_short | Correction of Hypothyroidism Seems to Have No Effect on Body Fat |
| title_sort | correction of hypothyroidism seems to have no effect on body fat |
| url | http://dx.doi.org/10.1155/2013/576794 |
| work_keys_str_mv | AT okanbakiner correctionofhypothyroidismseemstohavenoeffectonbodyfat AT emrebozkirli correctionofhypothyroidismseemstohavenoeffectonbodyfat AT emineduyguersozlubozkirli correctionofhypothyroidismseemstohavenoeffectonbodyfat AT kursatozsahin correctionofhypothyroidismseemstohavenoeffectonbodyfat |