123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome
123-Iodine metaiodobenzylguanidine (I-123 MIBG) imaging is frequently used in the assessment of sympathetic innervation and autonomic dysfunction in patients with cardiac failure, neurodegenerative Parkinson's syndrome, multiple system atrophy, myotonic dystrophy, and diabetic mellitus. The eti...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-09-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750387 |
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| _version_ | 1849324887651385344 |
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| author | Amit Bhoil Sobhan Vinjamuri |
| author_facet | Amit Bhoil Sobhan Vinjamuri |
| author_sort | Amit Bhoil |
| collection | DOAJ |
| description | 123-Iodine metaiodobenzylguanidine (I-123 MIBG) imaging is frequently used in the assessment of sympathetic innervation and autonomic dysfunction in patients with cardiac failure, neurodegenerative Parkinson's syndrome, multiple system atrophy, myotonic dystrophy, and diabetic mellitus. The etiology of pseudo-obstruction remains unknown with likely imbalance between sympathetic and parasympathetic innervation proposed as a hypothesis. We present a case demonstrating the utility of I-123 MIBG scintigraphy for evaluating a case of pseudo-obstruction requiring frequent hospitalization due to progressive complex autoimmune neurological disorder. |
| format | Article |
| id | doaj-art-d092332a28eb4472a5459b71a8e33d10 |
| institution | Kabale University |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-d092332a28eb4472a5459b71a8e33d102025-08-20T03:48:32ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122022-09-0110.1055/s-0042-1750387123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's SyndromeAmit Bhoil0Sobhan Vinjamuri1Department of Nuclear Medicine, The Royal Liverpool University Hospital NHS Trust, Liverpool, United KingdomDepartment of Nuclear Medicine, The Royal Liverpool University Hospital NHS Trust, Liverpool, United Kingdom123-Iodine metaiodobenzylguanidine (I-123 MIBG) imaging is frequently used in the assessment of sympathetic innervation and autonomic dysfunction in patients with cardiac failure, neurodegenerative Parkinson's syndrome, multiple system atrophy, myotonic dystrophy, and diabetic mellitus. The etiology of pseudo-obstruction remains unknown with likely imbalance between sympathetic and parasympathetic innervation proposed as a hypothesis. We present a case demonstrating the utility of I-123 MIBG scintigraphy for evaluating a case of pseudo-obstruction requiring frequent hospitalization due to progressive complex autoimmune neurological disorder.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750387i-123 mibgautonomic neuropathyogilvie's syndromepseudo-obstructionsympathetic dysfunction |
| spellingShingle | Amit Bhoil Sobhan Vinjamuri 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome World Journal of Nuclear Medicine i-123 mibg autonomic neuropathy ogilvie's syndrome pseudo-obstruction sympathetic dysfunction |
| title | 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome |
| title_full | 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome |
| title_fullStr | 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome |
| title_full_unstemmed | 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome |
| title_short | 123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome |
| title_sort | 123 iodine mibg in the assessment of sympathetic denervation in ogilvie s syndrome |
| topic | i-123 mibg autonomic neuropathy ogilvie's syndrome pseudo-obstruction sympathetic dysfunction |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750387 |
| work_keys_str_mv | AT amitbhoil 123iodinemibgintheassessmentofsympatheticdenervationinogilviessyndrome AT sobhanvinjamuri 123iodinemibgintheassessmentofsympatheticdenervationinogilviessyndrome |