New immunomodulatory treatment protocol for canine leishmaniosis reduces parasitemia and proteinuria.

New immunomodulatory treatment protocol for canine leishmaniosis reduces parasitemia and proteinuria.

The current standard treatment for canine leishmaniosis (CanL), N-methylglucamine antimoniate (MGA) given with allopurinol, is not fully effective and may cause adverse effects and drug resistance. In vitro and in vivo studies have shown that nucleotides, administered alone or with AHCC, offer benef...

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Main Authors: Guadalupe Miró, Sergi Segarra, José Joaquín Cerón, Lluís Ferrer, Laia Solano-Gallego, Laia Montell, Ester Costa, Joan Teichenne, Roger Mariné-Casadó, GALILEI trial Group, Xavier Roura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012712
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