Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study

Introduction: Despite solid preventive strategies to reduce the risk of hepatitis B virus (HBV) infection, recent reports about its prevalence and predictors are lacking in several Saudi cities at the community level. This study aimed to assess the seroprevalence of HBV and to identify the most impo...

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Main Authors: Rajaa M Al-Raddadi, Noha A Dashash, Hani A Alghamdi, Hanan S Alzahrani, Abdullah J Alsahafi, Abdullah M Algarni, Zeyad M AlRaddadi, Majed M Alghamdi, Raghad F Hakim, Abdulmohsen Hamdan Al-Zalabani
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2016-10-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/7880
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author Rajaa M Al-Raddadi
Noha A Dashash
Hani A Alghamdi
Hanan S Alzahrani
Abdullah J Alsahafi
Abdullah M Algarni
Zeyad M AlRaddadi
Majed M Alghamdi
Raghad F Hakim
Abdulmohsen Hamdan Al-Zalabani
author_facet Rajaa M Al-Raddadi
Noha A Dashash
Hani A Alghamdi
Hanan S Alzahrani
Abdullah J Alsahafi
Abdullah M Algarni
Zeyad M AlRaddadi
Majed M Alghamdi
Raghad F Hakim
Abdulmohsen Hamdan Al-Zalabani
author_sort Rajaa M Al-Raddadi
collection DOAJ
description Introduction: Despite solid preventive strategies to reduce the risk of hepatitis B virus (HBV) infection, recent reports about its prevalence and predictors are lacking in several Saudi cities at the community level. This study aimed to assess the seroprevalence of HBV and to identify the most important predictors among the Saudi population in Jeddah city, Saudi Arabia. Methodology: A cross-sectional study was conducted among 5,584 Saudi people attending primary health-care centers in Jeddah city during 2012/2013. Sociodemographic and hepatitis-related data were collected. HBV was diagnosed by ELISA test. The seroprevalence of HBV was estimated, and appropriate statistical analyses were performed, including univariate and multivariable regression analyses. Results: The seroprevalence of HBV was 2.2% (95% CI = 1.82–2.58) in the studied participants. The prevalence was higher among non-governmental workers (3.5%), male participants (3.4%) and those aged ≥ 25 years (2.4%). The most important predictors for increasing the risk of HBV in this study were HBV contacts, male sex, history of dental procedures and blood transfusion. The significant positive risks associated with these predictors were 3.3, 2.5, 2.0 and 1.65, respectively. HBV vaccination, on the other hand, was associated with a significant risk reduction of 88% (OR = 0.12; 95% CI = 0.03–0.51). Conclusions: The seroprevalence of HBV was relatively low among the Saudi population in Jeddah city reflecting the actions taken by health authorities to control HBV infection. However, more efforts, particularly in relation to health education programmes, strict control of blood banks and dental clinics, are still needed.
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spelling doaj-art-d07a3d679559482e813737cae4ac497c2025-08-20T02:16:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-10-01101010.3855/jidc.7880Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence studyRajaa M Al-Raddadi0Noha A Dashash1Hani A Alghamdi2Hanan S Alzahrani3Abdullah J Alsahafi4Abdullah M Algarni5Zeyad M AlRaddadi6Majed M Alghamdi7Raghad F Hakim8Abdulmohsen Hamdan Al-Zalabani9Ministry of Health, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Jeddah, Saudi ArabiaMinistry of Health, Jeddah, Saudi ArabiaKing Abdulaziz University, Jeddah, Saudi ArabiaTaibah University, Madinah, Saudi ArabiaIntroduction: Despite solid preventive strategies to reduce the risk of hepatitis B virus (HBV) infection, recent reports about its prevalence and predictors are lacking in several Saudi cities at the community level. This study aimed to assess the seroprevalence of HBV and to identify the most important predictors among the Saudi population in Jeddah city, Saudi Arabia. Methodology: A cross-sectional study was conducted among 5,584 Saudi people attending primary health-care centers in Jeddah city during 2012/2013. Sociodemographic and hepatitis-related data were collected. HBV was diagnosed by ELISA test. The seroprevalence of HBV was estimated, and appropriate statistical analyses were performed, including univariate and multivariable regression analyses. Results: The seroprevalence of HBV was 2.2% (95% CI = 1.82–2.58) in the studied participants. The prevalence was higher among non-governmental workers (3.5%), male participants (3.4%) and those aged ≥ 25 years (2.4%). The most important predictors for increasing the risk of HBV in this study were HBV contacts, male sex, history of dental procedures and blood transfusion. The significant positive risks associated with these predictors were 3.3, 2.5, 2.0 and 1.65, respectively. HBV vaccination, on the other hand, was associated with a significant risk reduction of 88% (OR = 0.12; 95% CI = 0.03–0.51). Conclusions: The seroprevalence of HBV was relatively low among the Saudi population in Jeddah city reflecting the actions taken by health authorities to control HBV infection. However, more efforts, particularly in relation to health education programmes, strict control of blood banks and dental clinics, are still needed. https://jidc.org/index.php/journal/article/view/7880Hepatitis Brisk factorsseroprevalenceSaudi Arabiainfectious diseasesepidemiology
spellingShingle Rajaa M Al-Raddadi
Noha A Dashash
Hani A Alghamdi
Hanan S Alzahrani
Abdullah J Alsahafi
Abdullah M Algarni
Zeyad M AlRaddadi
Majed M Alghamdi
Raghad F Hakim
Abdulmohsen Hamdan Al-Zalabani
Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
Journal of Infection in Developing Countries
Hepatitis B
risk factors
seroprevalence
Saudi Arabia
infectious diseases
epidemiology
title Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
title_full Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
title_fullStr Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
title_full_unstemmed Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
title_short Prevalence and predictors of hepatitis B in Jeddah City, Saudi Arabia: a population-based seroprevalence study
title_sort prevalence and predictors of hepatitis b in jeddah city saudi arabia a population based seroprevalence study
topic Hepatitis B
risk factors
seroprevalence
Saudi Arabia
infectious diseases
epidemiology
url https://jidc.org/index.php/journal/article/view/7880
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