Development of Hemispherical 3D Models of Human Brain and B Cell Lymphomas Using On-Chip Cell Dome System

Development of Hemispherical 3D Models of Human Brain and B Cell Lymphomas Using On-Chip Cell Dome System

Lymphocytes are generally non-adherent. This makes it challenging to fabricate three-dimensional (3D) structures mimicking the three-dimensional lymphoma microenvironment in vivo. This study presents the fabrication of a hemispherical 3D lymphoma model using the on-chip Cell Dome system with a hemis...

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Bibliographic Details
Main Authors: Ryotaro Kazama, Rina Ishikawa, Shinji Sakai
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
lymphoma
Cell Dome
3D cell cultures
tumor microenvironment
hypoxia
CD20
Online Access:https://www.mdpi.com/2306-5354/11/12/1303
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