<i>Folliculin</i> (<i>FLCN</i>) in Thyroid Tumors: Incidence, Significance, and Role as a Driver Gene and Secondary Alteration

<i>Folliculin</i> (<i>FLCN</i>) in Thyroid Tumors: Incidence, Significance, and Role as a Driver Gene and Secondary Alteration

Thyroid carcinomas are driven by diverse molecular alterations, but the tumor suppressor gene folliculin (<i>FLCN</i>), best known for its role in Birt–Hogg–Dubé (BHD) syndrome, has received limited attention in thyroid tumors. Here, we describe two thyroid tumors with pathogenic <i&g...

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Bibliographic Details
Main Authors: Faisal A. Hassan, Camryn Slone, Robert J. McDonald, Julie C. Dueber, Adeel M. Ashraf, Melina J. Windon, Oliver J. Fackelmayer, Cortney Y. Lee, Therese J. Bocklage, Derek B. Allison
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Current Oncology
Subjects:
thyroid cancer
molecular testing
Brit–Hogg–Dube
folliculin
preoperative molecular testing
Online Access:https://www.mdpi.com/1718-7729/32/4/224
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