Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis
Conclusions: Generally, HJXJ has the potential to reduce DKD injury and exerts anti-DKD effects by inhibiting the NLRP3-mediated NLRP3 inflammasome activation and pyroptosis in vitro and in vivo.
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2024/8772009 |
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| _version_ | 1849695592866906112 |
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| author | Zeng Zhang Yueping Bi Fengzhu Zhou Duanchun Zhang Siyu Xu Xinyi Zhang Zhaohua Fan Zheng Yao Yanming He |
| author_facet | Zeng Zhang Yueping Bi Fengzhu Zhou Duanchun Zhang Siyu Xu Xinyi Zhang Zhaohua Fan Zheng Yao Yanming He |
| author_sort | Zeng Zhang |
| collection | DOAJ |
| description | Conclusions: Generally, HJXJ has the potential to reduce DKD injury and exerts anti-DKD effects by inhibiting the NLRP3-mediated NLRP3 inflammasome activation and pyroptosis in vitro and in vivo. |
| format | Article |
| id | doaj-art-d05d4e1fdb9740828095bff85169c9de |
| institution | DOAJ |
| issn | 2314-6753 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-d05d4e1fdb9740828095bff85169c9de2025-08-20T03:19:43ZengWileyJournal of Diabetes Research2314-67532024-01-01202410.1155/2024/8772009Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and PyroptosisZeng Zhang0Yueping Bi1Fengzhu Zhou2Duanchun Zhang3Siyu Xu4Xinyi Zhang5Zhaohua Fan6Zheng Yao7Yanming He8Department of EndocrinologyDepartment of Chinese MedicineDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyConclusions: Generally, HJXJ has the potential to reduce DKD injury and exerts anti-DKD effects by inhibiting the NLRP3-mediated NLRP3 inflammasome activation and pyroptosis in vitro and in vivo.http://dx.doi.org/10.1155/2024/8772009 |
| spellingShingle | Zeng Zhang Yueping Bi Fengzhu Zhou Duanchun Zhang Siyu Xu Xinyi Zhang Zhaohua Fan Zheng Yao Yanming He Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Journal of Diabetes Research |
| title | Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis |
| title_full | Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis |
| title_fullStr | Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis |
| title_full_unstemmed | Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis |
| title_short | Huajuxiaoji Formula Alleviates Phenyl Sulfate-Induced Diabetic Kidney Disease by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis |
| title_sort | huajuxiaoji formula alleviates phenyl sulfate induced diabetic kidney disease by inhibiting nlrp3 inflammasome activation and pyroptosis |
| url | http://dx.doi.org/10.1155/2024/8772009 |
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