Adjuvantation of Kyasanur Forest Disease vaccine with TLR9 agonist CpG adjuvant enhances immunological efficacy and potency of the vaccine.

Adjuvantation of Kyasanur Forest Disease vaccine with TLR9 agonist CpG adjuvant enhances immunological efficacy and potency of the vaccine.

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The present study was carried out with the objectives of formulation of Kyasanur Forest Disease (KFD) vaccine adjuvanted with TLR9 agonist, CpG; evaluation of cell mediated and humoral immune response of CpG adjuvanted KFD vaccine in mice. The KFD seed virus (P9605) procured from ICMR-National Insti...

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Main Authors: Chandranaik B Marinaik, Bharath T Lakshmikanth, Chinmayie K Siddaramegowda, Apsana Rizwan, Amitha Reena Gomes, Keerthi Kaje, Doddamane Rathnamma, Shrikrishna Isloor, Archana M, Jagadish Hiremath, Raveendra Hegde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329348
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