Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in China

Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in China

Abstract Background Small airway dysfunction (SAD) is common but little is known about the longitudinal prognosis of spirometry-defined SAD. Therefore, we aimed to evaluate the risk of lung function decline and incident chronic obstructive pulmonary disease (COPD) of spirometry-defined SAD. Methods...

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Main Authors: Yumin Zhou, Fan Wu, Zhishan Deng, Zihui Wang, Heshen Tian, Peiyu Huang, Youlan Zheng, Huajing Yang, Ningning Zhao, Cuiqiong Dai, Changli Yang, Shuqing Yu, Jia Tian, Jiangyu Cui, Shengming Liu, Dali Wang, Xiaoping Wang, Jiachun Lu, Nanshan Zhong, Pixin Ran
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Respiratory Research
Subjects:
Small airway dysfunction
Spirometry
Lung function decline
Chronic obstructive pulmonary disease
Online Access:https://doi.org/10.1186/s12931-025-03244-3
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