Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy
Despite substantial improvements in survival rates for most cancers, pancreatic cancer still remains a leading cause of death from malignancy. The disease has no symptoms in the initial stages, it can early invade the surrounding organs, and treatment methods have poor long-term prognosis. In additi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-10-01
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| Series: | Journal of Mind and Medical Sciences |
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| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1564&context=jmms |
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| author | Adrian Silaghi Dragos Serban Bogdan Gaspar Valentin Verlas Dragos Epistatu Cristian Paius Roxana Sfetea Liliana Andronache Ioana Paunica Irina Ruxandra Strambu Daniela Gabriela Bălan Alexandru Florin Motofei Vlad Denis Constantin |
| author_facet | Adrian Silaghi Dragos Serban Bogdan Gaspar Valentin Verlas Dragos Epistatu Cristian Paius Roxana Sfetea Liliana Andronache Ioana Paunica Irina Ruxandra Strambu Daniela Gabriela Bălan Alexandru Florin Motofei Vlad Denis Constantin |
| author_sort | Adrian Silaghi |
| collection | DOAJ |
| description | Despite substantial improvements in survival rates for most cancers, pancreatic cancer still remains a leading cause of death from malignancy. The disease has no symptoms in the initial stages, it can early invade the surrounding organs, and treatment methods have poor long-term prognosis. In addition, this neoplasia is starting to be diagnosed more and more frequently in young people. High incidences have been found in developed regions such as Europe, North America, Australia, but recent data show that this condition is increasing in other regions as well. Pancreatic cancer involves multiple factors such as cigarette smoking, obesity, diabetes, alcohol consumption, inherited genetic factors, recent studies also correlating pancreatic cancer with abnormal metabolism of human microorganisms, blood type, as well as glucose and lipid levels. This review aims to update knowledge on the epidemiology, pathophysiology, diagnosis and treatment of pancreatic cancer. The goal is to encourage screening and early diagnosis methods, as well as to stimulate further research on this oncological topic, insufficiently studied to date. |
| format | Article |
| id | doaj-art-d04cfeb37b2f4b14a81aaf414d1066ad |
| institution | OA Journals |
| issn | 2392-7674 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj-art-d04cfeb37b2f4b14a81aaf414d1066ad2025-08-20T02:04:13ZengMDPI AGJournal of Mind and Medical Sciences2392-76742024-10-0111229930910.22543/2392-7674.1564Pancreatic cancer; from effective prevention and early diagnosis to personalized therapyAdrian Silaghi0Dragos Serban1Bogdan Gaspar2Valentin Verlas3Dragos Epistatu4Cristian Paius5Roxana Sfetea6Liliana Andronache7Ioana Paunica8Irina Ruxandra Strambu9Daniela Gabriela Bălan10Alexandru Florin Motofei11Vlad Denis Constantin12Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Department of Radiology, Bucharest, RomaniaSt. Pantelimon Emergency Clinical Hospital, Department of General Surgery, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Discipline of Modern Languages, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Discipline of Modern Languages, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, N.C. Paulescu National Institute, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaDespite substantial improvements in survival rates for most cancers, pancreatic cancer still remains a leading cause of death from malignancy. The disease has no symptoms in the initial stages, it can early invade the surrounding organs, and treatment methods have poor long-term prognosis. In addition, this neoplasia is starting to be diagnosed more and more frequently in young people. High incidences have been found in developed regions such as Europe, North America, Australia, but recent data show that this condition is increasing in other regions as well. Pancreatic cancer involves multiple factors such as cigarette smoking, obesity, diabetes, alcohol consumption, inherited genetic factors, recent studies also correlating pancreatic cancer with abnormal metabolism of human microorganisms, blood type, as well as glucose and lipid levels. This review aims to update knowledge on the epidemiology, pathophysiology, diagnosis and treatment of pancreatic cancer. The goal is to encourage screening and early diagnosis methods, as well as to stimulate further research on this oncological topic, insufficiently studied to date.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1564&context=jmmspancreatic cancerpreventionepidemiologypathophysiologydiagnosiscustomized therapy |
| spellingShingle | Adrian Silaghi Dragos Serban Bogdan Gaspar Valentin Verlas Dragos Epistatu Cristian Paius Roxana Sfetea Liliana Andronache Ioana Paunica Irina Ruxandra Strambu Daniela Gabriela Bălan Alexandru Florin Motofei Vlad Denis Constantin Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy Journal of Mind and Medical Sciences pancreatic cancer prevention epidemiology pathophysiology diagnosis customized therapy |
| title | Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy |
| title_full | Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy |
| title_fullStr | Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy |
| title_full_unstemmed | Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy |
| title_short | Pancreatic cancer; from effective prevention and early diagnosis to personalized therapy |
| title_sort | pancreatic cancer from effective prevention and early diagnosis to personalized therapy |
| topic | pancreatic cancer prevention epidemiology pathophysiology diagnosis customized therapy |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1564&context=jmms |
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