Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials

Abstract Social insects build robust nests to physically defend their colonies against attacks by predators and the intrusion of parasites and pathogens. While many previous studies on termite nests have focused on their physical defense functions, their nests also harbor various microorganisms that...

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Main Authors: Masaaki Nakashima, Kenji Matsuura
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-07667-2
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author Masaaki Nakashima
Kenji Matsuura
author_facet Masaaki Nakashima
Kenji Matsuura
author_sort Masaaki Nakashima
collection DOAJ
description Abstract Social insects build robust nests to physically defend their colonies against attacks by predators and the intrusion of parasites and pathogens. While many previous studies on termite nests have focused on their physical defense functions, their nests also harbor various microorganisms that play a role in maintaining the colony’s hygienic environment. In this study, we report a dynamic defense mechanism of termite nests, where termites bury pathogen-infected corpses into the nest material, enhancing the antimicrobial defense provided by symbiotic bacteria inhabiting the nest. Termites buried pathogen-infected corpses, which could pose a high pathogenic risk, into the nest material, while they cannibalized corpses that were non-infected. In nest material where corpses were buried, the abundance of Streptomyces, antibiotic-producing bacteria, increased and enhanced the antifungal activity of the nest material. Furthermore, this Streptomyces inhibited the growth of termite pathogens and improved worker survival rates in the presence of these pathogens. These results suggest that the interaction between termites and nest-associated symbiotic bacteria, facilitated by corpse burial, contributes to the continuous maintenance of nest hygiene. This study elucidates the function of the nest as a 'living defensive wall’ and enhances our understanding of the dynamic pathogen-defense systems employed by social insects.
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spelling doaj-art-d04831c6f1cc433fae2e8cb96ee8fe822025-08-20T03:37:20ZengNature PortfolioScientific Reports2045-23222025-07-0115111210.1038/s41598-025-07667-2Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materialsMasaaki Nakashima0Kenji Matsuura1Laboratory of Insect Ecology, Graduate School of Agriculture, Kyoto UniversityLaboratory of Insect Ecology, Graduate School of Agriculture, Kyoto UniversityAbstract Social insects build robust nests to physically defend their colonies against attacks by predators and the intrusion of parasites and pathogens. While many previous studies on termite nests have focused on their physical defense functions, their nests also harbor various microorganisms that play a role in maintaining the colony’s hygienic environment. In this study, we report a dynamic defense mechanism of termite nests, where termites bury pathogen-infected corpses into the nest material, enhancing the antimicrobial defense provided by symbiotic bacteria inhabiting the nest. Termites buried pathogen-infected corpses, which could pose a high pathogenic risk, into the nest material, while they cannibalized corpses that were non-infected. In nest material where corpses were buried, the abundance of Streptomyces, antibiotic-producing bacteria, increased and enhanced the antifungal activity of the nest material. Furthermore, this Streptomyces inhibited the growth of termite pathogens and improved worker survival rates in the presence of these pathogens. These results suggest that the interaction between termites and nest-associated symbiotic bacteria, facilitated by corpse burial, contributes to the continuous maintenance of nest hygiene. This study elucidates the function of the nest as a 'living defensive wall’ and enhances our understanding of the dynamic pathogen-defense systems employed by social insects.https://doi.org/10.1038/s41598-025-07667-2
spellingShingle Masaaki Nakashima
Kenji Matsuura
Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
Scientific Reports
title Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
title_full Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
title_fullStr Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
title_full_unstemmed Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
title_short Termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
title_sort termite antimicrobial defense through interaction with symbiotic microorganisms in nest materials
url https://doi.org/10.1038/s41598-025-07667-2
work_keys_str_mv AT masaakinakashima termiteantimicrobialdefensethroughinteractionwithsymbioticmicroorganismsinnestmaterials
AT kenjimatsuura termiteantimicrobialdefensethroughinteractionwithsymbioticmicroorganismsinnestmaterials