Endometrial Stem Cells and Reproduction

Abnormal endometrial function remains a significant cause of implantation failure, recurrent pregnancy loss, and other pathologies responsible for female infertility. The development of novel therapies to treat infertility due to endometrial dysfunction requires an understanding of the latest advanc...

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Main Authors: Sara S. Morelli, Pauline Yi, Laura T. Goldsmith
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2012/851367
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author Sara S. Morelli
Pauline Yi
Laura T. Goldsmith
author_facet Sara S. Morelli
Pauline Yi
Laura T. Goldsmith
author_sort Sara S. Morelli
collection DOAJ
description Abnormal endometrial function remains a significant cause of implantation failure, recurrent pregnancy loss, and other pathologies responsible for female infertility. The development of novel therapies to treat infertility due to endometrial dysfunction requires an understanding of the latest advancements in endometrial cell biology, such as the role of endometrial stem cells. The remarkable regenerative capacity of the human endometrium is absolutely essential for successful reproduction and likely requires a population of stem cells in the endometrium. The purpose of this review is to provide an introduction to some of the newest concepts in endometrial stem cell biology.
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institution Kabale University
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publishDate 2012-01-01
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series Obstetrics and Gynecology International
spelling doaj-art-d045c04748434958b54f0df520ebc0532025-02-03T01:20:51ZengWileyObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/851367851367Endometrial Stem Cells and ReproductionSara S. Morelli0Pauline Yi1Laura T. Goldsmith2Department of Obstetrics, Gynecology and Women’s Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USADepartment of Obstetrics, Gynecology and Women’s Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USADepartment of Obstetrics, Gynecology and Women’s Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USAAbnormal endometrial function remains a significant cause of implantation failure, recurrent pregnancy loss, and other pathologies responsible for female infertility. The development of novel therapies to treat infertility due to endometrial dysfunction requires an understanding of the latest advancements in endometrial cell biology, such as the role of endometrial stem cells. The remarkable regenerative capacity of the human endometrium is absolutely essential for successful reproduction and likely requires a population of stem cells in the endometrium. The purpose of this review is to provide an introduction to some of the newest concepts in endometrial stem cell biology.http://dx.doi.org/10.1155/2012/851367
spellingShingle Sara S. Morelli
Pauline Yi
Laura T. Goldsmith
Endometrial Stem Cells and Reproduction
Obstetrics and Gynecology International
title Endometrial Stem Cells and Reproduction
title_full Endometrial Stem Cells and Reproduction
title_fullStr Endometrial Stem Cells and Reproduction
title_full_unstemmed Endometrial Stem Cells and Reproduction
title_short Endometrial Stem Cells and Reproduction
title_sort endometrial stem cells and reproduction
url http://dx.doi.org/10.1155/2012/851367
work_keys_str_mv AT sarasmorelli endometrialstemcellsandreproduction
AT paulineyi endometrialstemcellsandreproduction
AT lauratgoldsmith endometrialstemcellsandreproduction