Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones

Aurones are natural bioactive dyes found in plants, and many of them are biologically active. We reported herein that α,β-dicarbonyl compounds condense with 3-coumarones without a solvent under microwave irradiation with clay as a catalyst. Novel acylaurones were obtained in good yields; the more st...

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Main Authors: Karima Boussafi, Didier Villemin, Nathalie Bar
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/14/1/32
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author Karima Boussafi
Didier Villemin
Nathalie Bar
author_facet Karima Boussafi
Didier Villemin
Nathalie Bar
author_sort Karima Boussafi
collection DOAJ
description Aurones are natural bioactive dyes found in plants, and many of them are biologically active. We reported herein that α,β-dicarbonyl compounds condense with 3-coumarones without a solvent under microwave irradiation with clay as a catalyst. Novel acylaurones were obtained in good yields; the more stable <i>E</i>-isomer was formed stereoselectively.
format Article
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issn 2673-4583
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publishDate 2023-11-01
publisher MDPI AG
record_format Article
series Chemistry Proceedings
spelling doaj-art-d0420299bf654296bd3b554ab6fb7ad02025-08-20T02:56:06ZengMDPI AGChemistry Proceedings2673-45832023-11-011413210.3390/ecsoc-27-16154Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-AuronesKarima Boussafi0Didier Villemin1Nathalie Bar2Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, INC3M, FR 3038, ENSICAEN et Université de Caen Normandie, 14050 Caen, FranceLaboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, INC3M, FR 3038, ENSICAEN et Université de Caen Normandie, 14050 Caen, FranceLaboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, INC3M, FR 3038, ENSICAEN et Université de Caen Normandie, 14050 Caen, FranceAurones are natural bioactive dyes found in plants, and many of them are biologically active. We reported herein that α,β-dicarbonyl compounds condense with 3-coumarones without a solvent under microwave irradiation with clay as a catalyst. Novel acylaurones were obtained in good yields; the more stable <i>E</i>-isomer was formed stereoselectively.https://www.mdpi.com/2673-4583/14/1/32auroneclay catalysiscoumaranonemicrowave
spellingShingle Karima Boussafi
Didier Villemin
Nathalie Bar
Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
Chemistry Proceedings
aurone
clay catalysis
coumaranone
microwave
title Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
title_full Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
title_fullStr Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
title_full_unstemmed Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
title_short Clay Catalysis: Solventless Condensation of Benzofuran-3(<i>2H</i>)-One with α,β-Dicarbonyl Compounds under Microwave Irradiation: Synthesis of New Acyl-Aurones
title_sort clay catalysis solventless condensation of benzofuran 3 i 2h i one with α β dicarbonyl compounds under microwave irradiation synthesis of new acyl aurones
topic aurone
clay catalysis
coumaranone
microwave
url https://www.mdpi.com/2673-4583/14/1/32
work_keys_str_mv AT karimaboussafi claycatalysissolventlesscondensationofbenzofuran3i2hionewithabdicarbonylcompoundsundermicrowaveirradiationsynthesisofnewacylaurones
AT didiervillemin claycatalysissolventlesscondensationofbenzofuran3i2hionewithabdicarbonylcompoundsundermicrowaveirradiationsynthesisofnewacylaurones
AT nathaliebar claycatalysissolventlesscondensationofbenzofuran3i2hionewithabdicarbonylcompoundsundermicrowaveirradiationsynthesisofnewacylaurones