A Biochemical Analysis of Patients with COVID-19 Infection
Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterations of the most common biochemical markers that...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Biochemistry Research International |
| Online Access: | http://dx.doi.org/10.1155/2021/1383830 |
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| author | Adil R. Sarhan Thaer A. Hussein Mohammed H. Flaih Khwam R. Hussein |
| author_facet | Adil R. Sarhan Thaer A. Hussein Mohammed H. Flaih Khwam R. Hussein |
| author_sort | Adil R. Sarhan |
| collection | DOAJ |
| description | Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterations of the most common biochemical markers that are reported in patients with COVID-19 still has not been well established. Here, we report clinical and blood biochemical indicators of 100 patients with COVID-19. Throat-swab upper respiratory samples were obtained from patients and real-time PCR was used to confirm SARS-CoV-2 infection. Gender, age, and clinical features such as diabetes mellitus, hypertension, and smoking habits were investigated. Biochemical parameters were categorized and analyzed according to these clinical characteristics. Triglycerides, GPT, and ALP are the biochemical markers that changed the most in the group of hypertension patients. Cholesterol and triglycerides were significantly different (P=0.01; P=0.04, respectively) between diabetic and nondiabetic patients with COVID-19. Potassium levels were significantly different (P=0.03) when comparing smokers with nonsmoker patients. Our results suggest several potential biochemical indexes that changed in patients with COVID-19 and whether certain comorbidity and clinical characteristics influence these markers. |
| format | Article |
| id | doaj-art-d03eda06c1ca4d8a98cb0a7da84cd7c0 |
| institution | DOAJ |
| issn | 2090-2247 2090-2255 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Biochemistry Research International |
| spelling | doaj-art-d03eda06c1ca4d8a98cb0a7da84cd7c02025-08-20T03:19:45ZengWileyBiochemistry Research International2090-22472090-22552021-01-01202110.1155/2021/13838301383830A Biochemical Analysis of Patients with COVID-19 InfectionAdil R. Sarhan0Thaer A. Hussein1Mohammed H. Flaih2Khwam R. Hussein3Department of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, IraqDepartment of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, IraqDepartment of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, IraqDepartment of Medical Laboratory Techniques, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah 64001, IraqSeveral studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterations of the most common biochemical markers that are reported in patients with COVID-19 still has not been well established. Here, we report clinical and blood biochemical indicators of 100 patients with COVID-19. Throat-swab upper respiratory samples were obtained from patients and real-time PCR was used to confirm SARS-CoV-2 infection. Gender, age, and clinical features such as diabetes mellitus, hypertension, and smoking habits were investigated. Biochemical parameters were categorized and analyzed according to these clinical characteristics. Triglycerides, GPT, and ALP are the biochemical markers that changed the most in the group of hypertension patients. Cholesterol and triglycerides were significantly different (P=0.01; P=0.04, respectively) between diabetic and nondiabetic patients with COVID-19. Potassium levels were significantly different (P=0.03) when comparing smokers with nonsmoker patients. Our results suggest several potential biochemical indexes that changed in patients with COVID-19 and whether certain comorbidity and clinical characteristics influence these markers.http://dx.doi.org/10.1155/2021/1383830 |
| spellingShingle | Adil R. Sarhan Thaer A. Hussein Mohammed H. Flaih Khwam R. Hussein A Biochemical Analysis of Patients with COVID-19 Infection Biochemistry Research International |
| title | A Biochemical Analysis of Patients with COVID-19 Infection |
| title_full | A Biochemical Analysis of Patients with COVID-19 Infection |
| title_fullStr | A Biochemical Analysis of Patients with COVID-19 Infection |
| title_full_unstemmed | A Biochemical Analysis of Patients with COVID-19 Infection |
| title_short | A Biochemical Analysis of Patients with COVID-19 Infection |
| title_sort | biochemical analysis of patients with covid 19 infection |
| url | http://dx.doi.org/10.1155/2021/1383830 |
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