Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge

Uterine malignancies are one of the prevalent causes of mortality and morbidity in women of peri- and postmenopausal age groups. The first approach in evaluating postmenopausal bleeding is sonological evaluation, where thickened endometrium is the usual finding, but it is not particularly diagnostic...

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Main Authors: Sharath Soman, R. Aruna Geethanjali, Brindha Prabhakaran, L. Priyadharshini, S. Vinobha, C. Jayasudha
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Current Medical Issues
Subjects:
Online Access:https://journals.lww.com/10.4103/cmi.cmi_40_25
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author Sharath Soman
R. Aruna Geethanjali
Brindha Prabhakaran
L. Priyadharshini
S. Vinobha
C. Jayasudha
author_facet Sharath Soman
R. Aruna Geethanjali
Brindha Prabhakaran
L. Priyadharshini
S. Vinobha
C. Jayasudha
author_sort Sharath Soman
collection DOAJ
description Uterine malignancies are one of the prevalent causes of mortality and morbidity in women of peri- and postmenopausal age groups. The first approach in evaluating postmenopausal bleeding is sonological evaluation, where thickened endometrium is the usual finding, but it is not particularly diagnostic of any pathology. One of the commonly employed strategies to help with timely diagnosis and treatment is endometrial biopsy. Despite such efforts, some entities are more difficult to diagnose due to various condition-specific characteristics, such as carcinosarcoma and adenosarcoma. This case series highlights a few such entities that have created difficulties for pathologists in the course of histopathological evaluation and clinicians in decision-making in management.
format Article
id doaj-art-d03ca884a2b4463a8840086dc95183d3
institution Kabale University
issn 0973-4651
2666-4054
language English
publishDate 2025-07-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Current Medical Issues
spelling doaj-art-d03ca884a2b4463a8840086dc95183d32025-08-20T04:02:14ZengWolters Kluwer Medknow PublicationsCurrent Medical Issues0973-46512666-40542025-07-0123322523110.4103/cmi.cmi_40_25Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic ChallengeSharath SomanR. Aruna GeethanjaliBrindha PrabhakaranL. PriyadharshiniS. VinobhaC. JayasudhaUterine malignancies are one of the prevalent causes of mortality and morbidity in women of peri- and postmenopausal age groups. The first approach in evaluating postmenopausal bleeding is sonological evaluation, where thickened endometrium is the usual finding, but it is not particularly diagnostic of any pathology. One of the commonly employed strategies to help with timely diagnosis and treatment is endometrial biopsy. Despite such efforts, some entities are more difficult to diagnose due to various condition-specific characteristics, such as carcinosarcoma and adenosarcoma. This case series highlights a few such entities that have created difficulties for pathologists in the course of histopathological evaluation and clinicians in decision-making in management.https://journals.lww.com/10.4103/cmi.cmi_40_25endometrial biopsyepithelial-mesenchymal neoplasmspostmenopausal bleedingthickened endometrium
spellingShingle Sharath Soman
R. Aruna Geethanjali
Brindha Prabhakaran
L. Priyadharshini
S. Vinobha
C. Jayasudha
Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
Current Medical Issues
endometrial biopsy
epithelial-mesenchymal neoplasms
postmenopausal bleeding
thickened endometrium
title Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
title_full Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
title_fullStr Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
title_full_unstemmed Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
title_short Elusive Entities of the Uterus Involving the Endometrium: A Diagnostic Challenge
title_sort elusive entities of the uterus involving the endometrium a diagnostic challenge
topic endometrial biopsy
epithelial-mesenchymal neoplasms
postmenopausal bleeding
thickened endometrium
url https://journals.lww.com/10.4103/cmi.cmi_40_25
work_keys_str_mv AT sharathsoman elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge
AT rarunageethanjali elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge
AT brindhaprabhakaran elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge
AT lpriyadharshini elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge
AT svinobha elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge
AT cjayasudha elusiveentitiesoftheuterusinvolvingtheendometriumadiagnosticchallenge