Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We pre...

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Main Authors: Astrid-Helene Ravn Jørgensen, Yiqiu Yao, Simon Francis Thomsen
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2018/8685136
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author Astrid-Helene Ravn Jørgensen
Yiqiu Yao
Simon Francis Thomsen
author_facet Astrid-Helene Ravn Jørgensen
Yiqiu Yao
Simon Francis Thomsen
author_sort Astrid-Helene Ravn Jørgensen
collection DOAJ
description Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).
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institution Kabale University
issn 2090-6463
2090-6471
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Dermatological Medicine
spelling doaj-art-d03aee1cd5ec41d09dfe9349346977fa2025-02-03T06:44:44ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712018-01-01201810.1155/2018/86851368685136Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis SuppurativaAstrid-Helene Ravn Jørgensen0Yiqiu Yao1Simon Francis Thomsen2Department of Dermato-Venereology and Wound Healing Centre, Bispebjerg Hospital, Copenhagen, DenmarkDepartment of Dermato-Venereology and Wound Healing Centre, Bispebjerg Hospital, Copenhagen, DenmarkDepartment of Dermato-Venereology and Wound Healing Centre, Bispebjerg Hospital, Copenhagen, DenmarkHidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).http://dx.doi.org/10.1155/2018/8685136
spellingShingle Astrid-Helene Ravn Jørgensen
Yiqiu Yao
Simon Francis Thomsen
Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
Case Reports in Dermatological Medicine
title Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_full Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_fullStr Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_full_unstemmed Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_short Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_sort therapeutic response to secukinumab in a 36 year old woman with hidradenitis suppurativa
url http://dx.doi.org/10.1155/2018/8685136
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AT simonfrancisthomsen therapeuticresponsetosecukinumabina36yearoldwomanwithhidradenitissuppurativa