Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation
Objective. The aim of this study was to determine the posterior cranial fossa volume, cerebellar volume, and herniated tonsillar volume in patients with chiari type I malformation and control subjects using stereological methods. Material and Methods. These volumes were estimated retrospectively usi...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/616934 |
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| author | Ümit Erkan Vurdem Niyazi Acer Tolga Ertekin Ahmet Savranlar Mehmet Fatih İnci |
| author_facet | Ümit Erkan Vurdem Niyazi Acer Tolga Ertekin Ahmet Savranlar Mehmet Fatih İnci |
| author_sort | Ümit Erkan Vurdem |
| collection | DOAJ |
| description | Objective. The aim of this study was to determine the posterior cranial fossa volume, cerebellar volume, and herniated tonsillar volume in patients with chiari type I malformation and control subjects using stereological methods. Material and Methods. These volumes were estimated retrospectively using the Cavalieri principle as a point-counting technique. We used magnetic resonance images taken from 25 control subjects and 30 patients with chiari type I malformation. Results. The posterior cranial fossa volume in patients with chiari type I malformation was significantly smaller than the volume in the control subjects (P<0.05). In the chiari type I malformation group, the cerebellar volume was smaller than the control group, but this difference was not statistically significant (P>0.05). In the chiari type I malformation group, the ratio of cerebellar volume to posterior cranial fossa volume was higher than in the control group. We also found a positive correlation between the posterior cranial fossa volume and cerebellar volume for each of the groups (r=0.865, P<0.001). The mean (±SD) herniated tonsillar volume and length were 0.89±0.50 cm3 and 9.63±3.37 mm in the chiari type I malformation group, respectively. Conclusion. This study has shown that posterior cranial fossa and cerebellum volumes can be measured by stereological methods, and the ratio of these measurements can contribute to the evaluation of chiari type I malformation cases. |
| format | Article |
| id | doaj-art-d0329312c49b4a6ba5622d3fc5ec5c8b |
| institution | DOAJ |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-d0329312c49b4a6ba5622d3fc5ec5c8b2025-08-20T03:19:46ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/616934616934Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I MalformationÜmit Erkan Vurdem0Niyazi Acer1Tolga Ertekin2Ahmet Savranlar3Mehmet Fatih İnci4Department of Radiology, Kayseri Education and Research Hospital, 38010 Kayseri, TurkeyDepartment of Anatomy, Erciyes University School of Medicine, 38039 Kayseri, TurkeyDepartment of Anatomy, Erciyes University School of Medicine, 38039 Kayseri, TurkeyDepartment of Radiology, Kayseri Education and Research Hospital, 38010 Kayseri, TurkeyDepartment of Radiology, Elazığ Harput State Hospital, 23200 Elazığ, TurkeyObjective. The aim of this study was to determine the posterior cranial fossa volume, cerebellar volume, and herniated tonsillar volume in patients with chiari type I malformation and control subjects using stereological methods. Material and Methods. These volumes were estimated retrospectively using the Cavalieri principle as a point-counting technique. We used magnetic resonance images taken from 25 control subjects and 30 patients with chiari type I malformation. Results. The posterior cranial fossa volume in patients with chiari type I malformation was significantly smaller than the volume in the control subjects (P<0.05). In the chiari type I malformation group, the cerebellar volume was smaller than the control group, but this difference was not statistically significant (P>0.05). In the chiari type I malformation group, the ratio of cerebellar volume to posterior cranial fossa volume was higher than in the control group. We also found a positive correlation between the posterior cranial fossa volume and cerebellar volume for each of the groups (r=0.865, P<0.001). The mean (±SD) herniated tonsillar volume and length were 0.89±0.50 cm3 and 9.63±3.37 mm in the chiari type I malformation group, respectively. Conclusion. This study has shown that posterior cranial fossa and cerebellum volumes can be measured by stereological methods, and the ratio of these measurements can contribute to the evaluation of chiari type I malformation cases.http://dx.doi.org/10.1100/2012/616934 |
| spellingShingle | Ümit Erkan Vurdem Niyazi Acer Tolga Ertekin Ahmet Savranlar Mehmet Fatih İnci Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation The Scientific World Journal |
| title | Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation |
| title_full | Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation |
| title_fullStr | Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation |
| title_full_unstemmed | Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation |
| title_short | Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation |
| title_sort | analysis of the volumes of the posterior cranial fossa cerebellum and herniated tonsils using the stereological methods in patients with chiari type i malformation |
| url | http://dx.doi.org/10.1100/2012/616934 |
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