A valuable test for malignancy of orbital tumors
Objective: This study determined the effectiveness of fine-needle aspiration biopsy (FNAB) in detecting malignancy in orbital lesions compared with section biopsy. Its sensitivity, specificity, and positive predictive value were determined. Methods: This is a nonrandomized, prospective, comparati...
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| Language: | English |
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Philippine Academy of Ophthalmology
2004-12-01
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| Series: | Philippine Journal of Ophthalmology |
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| Online Access: | https://paojournal.com/index.php/pjo/article/view/433 |
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| author | Alberto M. Castro, MD Gloria D. Lim, MD Lawrence Marlon H. Pe, MD |
| author_facet | Alberto M. Castro, MD Gloria D. Lim, MD Lawrence Marlon H. Pe, MD |
| author_sort | Alberto M. Castro, MD |
| collection | DOAJ |
| description | Objective: This study determined the effectiveness of fine-needle aspiration biopsy (FNAB) in detecting malignancy in orbital lesions compared with section biopsy. Its sensitivity, specificity, and positive predictive value were determined.
Methods: This is a nonrandomized, prospective, comparative study of 33 (20 males and 13 females, ages 11 months to 71 years) with orbital lesions who underwent FNAB. The cytologic results were correlated with the histologic results. Different pathologists who were blinded as to study lesions read the cytologic and histologic smears.
Results: Twenty-three patients whose smears had high yield of cells were included in the study. Excluded were 2 with poor yield smears, 3 hemorrhagic smears, and 5 without section biopsies of which 2 presented with pyogenic granuloma. FNAB is 87.5% sensitive and 100% specific, with a positive predictive value of 100%. No statistical difference was found between FNAB and section biopsy in detecting ocular malignancy (p < 0.05) in this study.
Conclusion: FNAB has a good sensitivity and specificity in diagnosing ocular malignancy and is a useful tool in the diagnosis of orbital tumors. |
| format | Article |
| id | doaj-art-d02f7bb7987f451da4d8ed860442ef67 |
| institution | DOAJ |
| issn | 0031-7659 |
| language | English |
| publishDate | 2004-12-01 |
| publisher | Philippine Academy of Ophthalmology |
| record_format | Article |
| series | Philippine Journal of Ophthalmology |
| spelling | doaj-art-d02f7bb7987f451da4d8ed860442ef672025-08-20T02:48:23ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592004-12-01294175177433A valuable test for malignancy of orbital tumorsAlberto M. Castro, MD0Gloria D. Lim, MD1Lawrence Marlon H. Pe, MD2East Avenue Medical Center Quezon City, PhilippinesEast Avenue Medical Center Quezon City, PhilippinesEast Avenue Medical Center Quezon City, PhilippinesObjective: This study determined the effectiveness of fine-needle aspiration biopsy (FNAB) in detecting malignancy in orbital lesions compared with section biopsy. Its sensitivity, specificity, and positive predictive value were determined. Methods: This is a nonrandomized, prospective, comparative study of 33 (20 males and 13 females, ages 11 months to 71 years) with orbital lesions who underwent FNAB. The cytologic results were correlated with the histologic results. Different pathologists who were blinded as to study lesions read the cytologic and histologic smears. Results: Twenty-three patients whose smears had high yield of cells were included in the study. Excluded were 2 with poor yield smears, 3 hemorrhagic smears, and 5 without section biopsies of which 2 presented with pyogenic granuloma. FNAB is 87.5% sensitive and 100% specific, with a positive predictive value of 100%. No statistical difference was found between FNAB and section biopsy in detecting ocular malignancy (p < 0.05) in this study. Conclusion: FNAB has a good sensitivity and specificity in diagnosing ocular malignancy and is a useful tool in the diagnosis of orbital tumors.https://paojournal.com/index.php/pjo/article/view/433fine-needle aspiration biopsysection biopsymalignancyorbital tumors |
| spellingShingle | Alberto M. Castro, MD Gloria D. Lim, MD Lawrence Marlon H. Pe, MD A valuable test for malignancy of orbital tumors Philippine Journal of Ophthalmology fine-needle aspiration biopsy section biopsy malignancy orbital tumors |
| title | A valuable test for malignancy of orbital tumors |
| title_full | A valuable test for malignancy of orbital tumors |
| title_fullStr | A valuable test for malignancy of orbital tumors |
| title_full_unstemmed | A valuable test for malignancy of orbital tumors |
| title_short | A valuable test for malignancy of orbital tumors |
| title_sort | valuable test for malignancy of orbital tumors |
| topic | fine-needle aspiration biopsy section biopsy malignancy orbital tumors |
| url | https://paojournal.com/index.php/pjo/article/view/433 |
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