Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies.

Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies.

Babies born clinically Small- or Large-for-Gestational-Age (SGA or LGA; sex- and gestational age-adjusted birth weight (BW) <10th or >90th percentile, respectively), are at higher risks of complications. SGA and LGA include babies who have experienced environment-related growth-restriction or...

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Main Authors: Robin N Beaumont, Sarah J Kotecha, Andrew R Wood, Bridget A Knight, Sylvain Sebert, Mark I McCarthy, Andrew T Hattersley, Marjo-Riitta Järvelin, Nicholas J Timpson, Rachel M Freathy, Sailesh Kotecha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009191&type=printable
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