FROP-1 peptide-conjugated ultrasmall superparamagnetic nanoparticles as a targeted T1-weighted MR contrast agent for breast cancer: in vitro study

FROP-1 peptide-conjugated ultrasmall superparamagnetic nanoparticles as a targeted T1-weighted MR contrast agent for breast cancer: in vitro study

Abstract Background The aim of this study was to produce ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs) conjugated to the FROP-1 peptide for targeted magnetic resonance imaging (MRI) of breast cancer cell lines and to evaluate its application as a specific and targeted T1-weight...

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Bibliographic Details
Main Authors: Melika Samari, Zahra Alamzadeh, Rasoul Irajirad, Abolfazl Sarikhani, Vahid Pirhajati Mahabadi, Habib Ghaznavi, Samideh Khoei
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biomedical Engineering
Subjects:
T1-weighted MRI
Breast cancer
Molecular imaging
FROP-1 peptide
SPIONs
Online Access:https://doi.org/10.1186/s42490-025-00091-7
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