Prevention of Preterm Labour: 2011 Update on Tocolysis

The aim of this paper is to review available data about drugs for preventing preterm labour. Tocolytic therapy includes β adrenergic receptor agonists, NO donors, magnesium sulphate, prostaglandin-synthase inhibitors, oxytocin receptor antagonists, calcium-channel blockers, progesterone, 17-α-hydrox...

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Main Authors: C. Hubinont, F. Debieve
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2011/941057
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author C. Hubinont
F. Debieve
author_facet C. Hubinont
F. Debieve
author_sort C. Hubinont
collection DOAJ
description The aim of this paper is to review available data about drugs for preventing preterm labour. Tocolytic therapy includes β adrenergic receptor agonists, NO donors, magnesium sulphate, prostaglandin-synthase inhibitors, oxytocin receptor antagonists, calcium-channel blockers, progesterone, 17-α-hydroxyprogesterone caproate, and antibiotics. Their specific effects on myometrial contractility, their safety, their efficiency, and side effects profile for the mother and the fetus are presented. The main question of why and for what reasons tocolysis should be administrated is discussed.
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institution Kabale University
issn 2090-2727
2090-2735
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publishDate 2011-01-01
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series Journal of Pregnancy
spelling doaj-art-d02541915d1647579f1130f3865c073e2025-02-03T05:51:55ZengWileyJournal of Pregnancy2090-27272090-27352011-01-01201110.1155/2011/941057941057Prevention of Preterm Labour: 2011 Update on TocolysisC. Hubinont0F. Debieve1Department of Obstetrics, Saint-Luc University Hospital, 10 Avenue Hippocrate, 1200 Bruxelles, BelgiumDepartment of Obstetrics, Saint-Luc University Hospital, 10 Avenue Hippocrate, 1200 Bruxelles, BelgiumThe aim of this paper is to review available data about drugs for preventing preterm labour. Tocolytic therapy includes β adrenergic receptor agonists, NO donors, magnesium sulphate, prostaglandin-synthase inhibitors, oxytocin receptor antagonists, calcium-channel blockers, progesterone, 17-α-hydroxyprogesterone caproate, and antibiotics. Their specific effects on myometrial contractility, their safety, their efficiency, and side effects profile for the mother and the fetus are presented. The main question of why and for what reasons tocolysis should be administrated is discussed.http://dx.doi.org/10.1155/2011/941057
spellingShingle C. Hubinont
F. Debieve
Prevention of Preterm Labour: 2011 Update on Tocolysis
Journal of Pregnancy
title Prevention of Preterm Labour: 2011 Update on Tocolysis
title_full Prevention of Preterm Labour: 2011 Update on Tocolysis
title_fullStr Prevention of Preterm Labour: 2011 Update on Tocolysis
title_full_unstemmed Prevention of Preterm Labour: 2011 Update on Tocolysis
title_short Prevention of Preterm Labour: 2011 Update on Tocolysis
title_sort prevention of preterm labour 2011 update on tocolysis
url http://dx.doi.org/10.1155/2011/941057
work_keys_str_mv AT chubinont preventionofpretermlabour2011updateontocolysis
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