Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography

Introduction: Photon-counting computed tomography (CT) is equipped with an adaptive iterative reconstruction method called quantum iterative reconstruction (QIR), which allows the intensity to be changed during image reconstruction. It is known that the reconstruction conditions of CT images affect...

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Main Authors: Miyu Ohata, Ryohei Fukui, Yusuke Morimitsu, Daichi Kobayashi, Takatsugu Yamauchi, Noriaki Akagi, Mitsugi Honda, Aiko Hayashi, Koshi Hasegawa, Katsuhiro Kida, Sachiko Goto, Takao Hiraki
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Medical Physics
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Online Access:https://journals.lww.com/10.4103/jmp.jmp_114_24
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author Miyu Ohata
Ryohei Fukui
Yusuke Morimitsu
Daichi Kobayashi
Takatsugu Yamauchi
Noriaki Akagi
Mitsugi Honda
Aiko Hayashi
Koshi Hasegawa
Katsuhiro Kida
Sachiko Goto
Takao Hiraki
author_facet Miyu Ohata
Ryohei Fukui
Yusuke Morimitsu
Daichi Kobayashi
Takatsugu Yamauchi
Noriaki Akagi
Mitsugi Honda
Aiko Hayashi
Koshi Hasegawa
Katsuhiro Kida
Sachiko Goto
Takao Hiraki
author_sort Miyu Ohata
collection DOAJ
description Introduction: Photon-counting computed tomography (CT) is equipped with an adaptive iterative reconstruction method called quantum iterative reconstruction (QIR), which allows the intensity to be changed during image reconstruction. It is known that the reconstruction conditions of CT images affect the analysis results when performing radiomic analysis. The aim of this study is to investigate the effect of QIR intensity on image quality and radiomic analysis of renal cell carcinoma (RCC). Materials and Methods: The QIR intensities were selected as off, 2 and 4. The image quality evaluation items considered were task-based transfer function (TTF), noise power spectrum (NPS), and low-contrast object specific contrast-to-noise ratio (CNRLO). The influence on radiomic analysis was assessed using the discrimination accuracy of clear cell RCC. Results: For image quality evaluation, TTF and NPS values were lower and CNRLO values were higher with increasing QIR intensity; for radiomic analysis, sensitivity, specificity, and accuracy were higher with increasing QIR intensity. Principal component analysis and receiver operating characteristics analysis also showed higher values with increasing QIR intensity. Conclusion: It was confirmed that the intensity of the QIR intensity affects both the image quality and the radiomic analysis.
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1998-3913
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publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
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spelling doaj-art-d0221f99d7fa4db4a0b664cf2efa85632025-08-20T02:16:03ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62031998-39132025-01-0150110010710.4103/jmp.jmp_114_24Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed TomographyMiyu OhataRyohei FukuiYusuke MorimitsuDaichi KobayashiTakatsugu YamauchiNoriaki AkagiMitsugi HondaAiko HayashiKoshi HasegawaKatsuhiro KidaSachiko GotoTakao HirakiIntroduction: Photon-counting computed tomography (CT) is equipped with an adaptive iterative reconstruction method called quantum iterative reconstruction (QIR), which allows the intensity to be changed during image reconstruction. It is known that the reconstruction conditions of CT images affect the analysis results when performing radiomic analysis. The aim of this study is to investigate the effect of QIR intensity on image quality and radiomic analysis of renal cell carcinoma (RCC). Materials and Methods: The QIR intensities were selected as off, 2 and 4. The image quality evaluation items considered were task-based transfer function (TTF), noise power spectrum (NPS), and low-contrast object specific contrast-to-noise ratio (CNRLO). The influence on radiomic analysis was assessed using the discrimination accuracy of clear cell RCC. Results: For image quality evaluation, TTF and NPS values were lower and CNRLO values were higher with increasing QIR intensity; for radiomic analysis, sensitivity, specificity, and accuracy were higher with increasing QIR intensity. Principal component analysis and receiver operating characteristics analysis also showed higher values with increasing QIR intensity. Conclusion: It was confirmed that the intensity of the QIR intensity affects both the image quality and the radiomic analysis.https://journals.lww.com/10.4103/jmp.jmp_114_24image qualityphoton-counting computed tomographyquantum iterative reconstructionradiomicsrenal cell carcinoma
spellingShingle Miyu Ohata
Ryohei Fukui
Yusuke Morimitsu
Daichi Kobayashi
Takatsugu Yamauchi
Noriaki Akagi
Mitsugi Honda
Aiko Hayashi
Koshi Hasegawa
Katsuhiro Kida
Sachiko Goto
Takao Hiraki
Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
Journal of Medical Physics
image quality
photon-counting computed tomography
quantum iterative reconstruction
radiomics
renal cell carcinoma
title Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
title_full Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
title_fullStr Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
title_full_unstemmed Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
title_short Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
title_sort investigating the effects of reconstruction conditions on image quality and radiomic analysis in photon counting computed tomography
topic image quality
photon-counting computed tomography
quantum iterative reconstruction
radiomics
renal cell carcinoma
url https://journals.lww.com/10.4103/jmp.jmp_114_24
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