Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate

Metastasis to the glans penis is a rare phenomenon and usually occurs in a late stage of disease. A 68-year-old man was referred to our clinic because of two indurated lesions of the glans penis and minor lower urinary tract symptoms. Digital rectal examination revealed a hard nodular prostate, and...

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Main Authors: S. Dijkstra, A. G. van der Heijden, H. E. Schaafsma, P. F. A. Mulders
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2012/193787
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author S. Dijkstra
A. G. van der Heijden
H. E. Schaafsma
P. F. A. Mulders
author_facet S. Dijkstra
A. G. van der Heijden
H. E. Schaafsma
P. F. A. Mulders
author_sort S. Dijkstra
collection DOAJ
description Metastasis to the glans penis is a rare phenomenon and usually occurs in a late stage of disease. A 68-year-old man was referred to our clinic because of two indurated lesions of the glans penis and minor lower urinary tract symptoms. Digital rectal examination revealed a hard nodular prostate, and serum prostate-specific antigen (sPSA) level was 13.3 ng/mL. Biopsies of the penile lesions and transrectal ultrasound-guided prostate biopsies were taken. Immunohistochemical staining of formalin-fixed paraffin-embedded tissue exposed a synchronous penile metastasis from a high-grade adenocarcinoma of the prostate. Except a pathologically enlarged lymph node detected with MRI there was no suspicion on other metastases. Currently this patient is being treated with a Gonadoreline (GnRH) antagonist. Nevertheless, the prognosis will be poor.
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publishDate 2012-01-01
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series Case Reports in Urology
spelling doaj-art-d01d473709124a69a8d754c4bf0919882025-08-20T03:19:43ZengWileyCase Reports in Urology2090-696X2090-69782012-01-01201210.1155/2012/193787193787Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the ProstateS. Dijkstra0A. G. van der Heijden1H. E. Schaafsma2P. F. A. Mulders3Department of Urology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB Nijmegen, The NetherlandsDepartment of Urology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB Nijmegen, The NetherlandsDepartment of Pathology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB Nijmegen, The NetherlandsDepartment of Urology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB Nijmegen, The NetherlandsMetastasis to the glans penis is a rare phenomenon and usually occurs in a late stage of disease. A 68-year-old man was referred to our clinic because of two indurated lesions of the glans penis and minor lower urinary tract symptoms. Digital rectal examination revealed a hard nodular prostate, and serum prostate-specific antigen (sPSA) level was 13.3 ng/mL. Biopsies of the penile lesions and transrectal ultrasound-guided prostate biopsies were taken. Immunohistochemical staining of formalin-fixed paraffin-embedded tissue exposed a synchronous penile metastasis from a high-grade adenocarcinoma of the prostate. Except a pathologically enlarged lymph node detected with MRI there was no suspicion on other metastases. Currently this patient is being treated with a Gonadoreline (GnRH) antagonist. Nevertheless, the prognosis will be poor.http://dx.doi.org/10.1155/2012/193787
spellingShingle S. Dijkstra
A. G. van der Heijden
H. E. Schaafsma
P. F. A. Mulders
Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
Case Reports in Urology
title Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
title_full Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
title_fullStr Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
title_full_unstemmed Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
title_short Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate
title_sort synchronous penile metastasis from a high grade adenocarcinoma of the prostate
url http://dx.doi.org/10.1155/2012/193787
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AT agvanderheijden synchronouspenilemetastasisfromahighgradeadenocarcinomaoftheprostate
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AT pfamulders synchronouspenilemetastasisfromahighgradeadenocarcinomaoftheprostate