Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms
The paper presents the results of studying the spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on their ability to form biofilms. Two methodological approaches were used to determine the causes of the low efficiency of antibiotic therapy used in livestock farm...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/32/bioconf_esdca2025_01020.pdf |
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| author | Denisenko T. E. Metla A. A. Minkova O. A. Yarygina E. I. |
| author_facet | Denisenko T. E. Metla A. A. Minkova O. A. Yarygina E. I. |
| author_sort | Denisenko T. E. |
| collection | DOAJ |
| description | The paper presents the results of studying the spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on their ability to form biofilms. Two methodological approaches were used to determine the causes of the low efficiency of antibiotic therapy used in livestock farms. The sensitivity of the isolated staphylococci to antibiotics was determined and the ability of these cultures to form biofilms was established. It was found that staphylococci isolated from goats were resistant mainly (more than 50% of isolates) to tylosin, penicillin, clindamycin, amikacin, lincomycin, gentamicin, meropenem and levofloxacin, from cattle - to azithromycin, clindamycin, meropenem, rifampicin, amikacin, and from poultry - to tylosin, penicillin, tetracycline, doxycycline, amikacin, azithromycin, clindamycin, ciprofloxacin, cefotaxime, lincomycin and gentamicin. It was found that all strains had multiple drug resistance to two or more groups of antibiotics. It was found that 60-67% of microorganism strains were potentially capable of forming biofilms. It has been proven that positive results of antibiotic susceptibility tests in vitro cannot be extrapolated to the predicted effectiveness of these drugs in vivo. The need to study isolated staphylococcal strains for antibiotic sensitivity and their ability to form a biofilm when selecting an optimal treatment regimen for farm animals and poultry is substantiated. |
| format | Article |
| id | doaj-art-d0144205de584fed89252c40d2eb105d |
| institution | DOAJ |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-d0144205de584fed89252c40d2eb105d2025-08-20T03:22:14ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011810102010.1051/bioconf/202518101020bioconf_esdca2025_01020Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilmsDenisenko T. E.0Metla A. A.1Minkova O. A.2Yarygina E. I.3Federal State Budgetary Educational Institution of Higher Education “Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Scriabin”Federal State Budgetary Educational Institution of Higher Education “Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Scriabin”Federal State Budgetary Educational Institution of Higher Education “Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Scriabin”Federal State Budgetary Educational Institution of Higher Education “Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Scriabin”The paper presents the results of studying the spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on their ability to form biofilms. Two methodological approaches were used to determine the causes of the low efficiency of antibiotic therapy used in livestock farms. The sensitivity of the isolated staphylococci to antibiotics was determined and the ability of these cultures to form biofilms was established. It was found that staphylococci isolated from goats were resistant mainly (more than 50% of isolates) to tylosin, penicillin, clindamycin, amikacin, lincomycin, gentamicin, meropenem and levofloxacin, from cattle - to azithromycin, clindamycin, meropenem, rifampicin, amikacin, and from poultry - to tylosin, penicillin, tetracycline, doxycycline, amikacin, azithromycin, clindamycin, ciprofloxacin, cefotaxime, lincomycin and gentamicin. It was found that all strains had multiple drug resistance to two or more groups of antibiotics. It was found that 60-67% of microorganism strains were potentially capable of forming biofilms. It has been proven that positive results of antibiotic susceptibility tests in vitro cannot be extrapolated to the predicted effectiveness of these drugs in vivo. The need to study isolated staphylococcal strains for antibiotic sensitivity and their ability to form a biofilm when selecting an optimal treatment regimen for farm animals and poultry is substantiated.https://www.bio-conferences.org/articles/bioconf/pdf/2025/32/bioconf_esdca2025_01020.pdf |
| spellingShingle | Denisenko T. E. Metla A. A. Minkova O. A. Yarygina E. I. Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms BIO Web of Conferences |
| title | Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms |
| title_full | Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms |
| title_fullStr | Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms |
| title_full_unstemmed | Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms |
| title_short | Spectrum of resistance to antibacterial drugs of Staphylococcus spp. isolates depending on the ability to form biofilms |
| title_sort | spectrum of resistance to antibacterial drugs of staphylococcus spp isolates depending on the ability to form biofilms |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/32/bioconf_esdca2025_01020.pdf |
| work_keys_str_mv | AT denisenkote spectrumofresistancetoantibacterialdrugsofstaphylococcussppisolatesdependingontheabilitytoformbiofilms AT metlaaa spectrumofresistancetoantibacterialdrugsofstaphylococcussppisolatesdependingontheabilitytoformbiofilms AT minkovaoa spectrumofresistancetoantibacterialdrugsofstaphylococcussppisolatesdependingontheabilitytoformbiofilms AT yaryginaei spectrumofresistancetoantibacterialdrugsofstaphylococcussppisolatesdependingontheabilitytoformbiofilms |