Diagnosis and therapy of parathyroid cysts: A review of 7 cases

Parathyroid cysts (PC) are relatively rare lesions in the neck. This study aims to present 7 new cases of PC and share our experience. Between September 2017 and December 2022, seven patients diagnosed with PCs underwent surgery. Relevant clinical data were collected. Five of the patients had non-fu...

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Main Authors: Zhiwei Zhou, Jingjia Li, Weixiong Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Acta Oto-Laryngologica Case Reports
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/23772484.2025.2470266
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author Zhiwei Zhou
Jingjia Li
Weixiong Chen
author_facet Zhiwei Zhou
Jingjia Li
Weixiong Chen
author_sort Zhiwei Zhou
collection DOAJ
description Parathyroid cysts (PC) are relatively rare lesions in the neck. This study aims to present 7 new cases of PC and share our experience. Between September 2017 and December 2022, seven patients diagnosed with PCs underwent surgery. Relevant clinical data were collected. Five of the patients had non-functioning parathyroid cysts (NPC) and the remaining two had functioning parathyroid cysts (FPC). Cystic fluid contained high level of parathyroid hormone (PTH). Histologically, NPCs were confirmed as true parathyroid cysts, while FPCs were attributed to cystic degeneration of parathyroid adenomas. Three cases showing elevated PTH level following surgery, however, it subsequently returned to normal in all these cases. No recurrence or abnormal calcium levels were reported during follow-up. In conclusion, PTH level in cystic fluid can aid in the diagnosis of PC. It is important to differentiate between NPC and FPC. Surgical excision is preferable for both types.
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series Acta Oto-Laryngologica Case Reports
spelling doaj-art-d012398c729d4c038c92a9428ec039632025-08-20T02:30:13ZengTaylor & Francis GroupActa Oto-Laryngologica Case Reports2377-24842025-12-01101313610.1080/23772484.2025.2470266Diagnosis and therapy of parathyroid cysts: A review of 7 casesZhiwei Zhou0Jingjia Li1Weixiong Chen2Department of Otorhinolaryngology-Head and Neck Surgery, First People’s Hospital of Foshan, Foshan, P.R. ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, First People’s Hospital of Foshan, Foshan, P.R. ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, First People’s Hospital of Foshan, Foshan, P.R. ChinaParathyroid cysts (PC) are relatively rare lesions in the neck. This study aims to present 7 new cases of PC and share our experience. Between September 2017 and December 2022, seven patients diagnosed with PCs underwent surgery. Relevant clinical data were collected. Five of the patients had non-functioning parathyroid cysts (NPC) and the remaining two had functioning parathyroid cysts (FPC). Cystic fluid contained high level of parathyroid hormone (PTH). Histologically, NPCs were confirmed as true parathyroid cysts, while FPCs were attributed to cystic degeneration of parathyroid adenomas. Three cases showing elevated PTH level following surgery, however, it subsequently returned to normal in all these cases. No recurrence or abnormal calcium levels were reported during follow-up. In conclusion, PTH level in cystic fluid can aid in the diagnosis of PC. It is important to differentiate between NPC and FPC. Surgical excision is preferable for both types.https://www.tandfonline.com/doi/10.1080/23772484.2025.2470266Parathyroid cystintracystic parathyroid hormonefunctioning and non-functioning
spellingShingle Zhiwei Zhou
Jingjia Li
Weixiong Chen
Diagnosis and therapy of parathyroid cysts: A review of 7 cases
Acta Oto-Laryngologica Case Reports
Parathyroid cyst
intracystic parathyroid hormone
functioning and non-functioning
title Diagnosis and therapy of parathyroid cysts: A review of 7 cases
title_full Diagnosis and therapy of parathyroid cysts: A review of 7 cases
title_fullStr Diagnosis and therapy of parathyroid cysts: A review of 7 cases
title_full_unstemmed Diagnosis and therapy of parathyroid cysts: A review of 7 cases
title_short Diagnosis and therapy of parathyroid cysts: A review of 7 cases
title_sort diagnosis and therapy of parathyroid cysts a review of 7 cases
topic Parathyroid cyst
intracystic parathyroid hormone
functioning and non-functioning
url https://www.tandfonline.com/doi/10.1080/23772484.2025.2470266
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