A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder

Objective. To describe a case of lung cancer with brain metastasis in a patient who developed new late-onset bipolar disorder 2 years previously. Background. The typical onset age of bipolar disorder is approximately 20, and the first episode is usually a depressive episode. It is still not clear wh...

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Main Authors: Shin-Heng Shen, Shwu-Hua Lee
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2021/8880539
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author Shin-Heng Shen
Shwu-Hua Lee
author_facet Shin-Heng Shen
Shwu-Hua Lee
author_sort Shin-Heng Shen
collection DOAJ
description Objective. To describe a case of lung cancer with brain metastasis in a patient who developed new late-onset bipolar disorder 2 years previously. Background. The typical onset age of bipolar disorder is approximately 20, and the first episode is usually a depressive episode. It is still not clear which age-specific factors contribute to the underlying risk. Materials and Methods. A 65-year-old male patient presented with a new-onset manic episode characterized by labile mood, impulsivity, decreased need for sleep, and grandiosity. He was diagnosed with late-onset bipolar disorder after excluding other possible physiological conditions. He was hospitalized in the acute psychiatric ward, and a combination of mood stabilizers and antipsychotics was prescribed. His mental condition improved, and he remained stable for 2 years. However, he experienced abrupt cognitive decline for 2 months and was referred to the emergency room for physiological examination. Results. The patient was diagnosed with lung cancer with brain metastasis by brain magnetic resonance imaging and whole-body positron emission tomography. Conclusion. In geriatric patients, who are at high risk of multiple medical conditions, excluding secondary causes of bipolar disorder is important.
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spelling doaj-art-d00ef2481b9c4c5d9814d1bed64ac8802025-02-03T06:46:46ZengWileyBehavioural Neurology0953-41801875-85842021-01-01202110.1155/2021/88805398880539A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar DisorderShin-Heng Shen0Shwu-Hua Lee1Department of Psychiatry, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, TaiwanDepartment of Psychiatry, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, TaiwanObjective. To describe a case of lung cancer with brain metastasis in a patient who developed new late-onset bipolar disorder 2 years previously. Background. The typical onset age of bipolar disorder is approximately 20, and the first episode is usually a depressive episode. It is still not clear which age-specific factors contribute to the underlying risk. Materials and Methods. A 65-year-old male patient presented with a new-onset manic episode characterized by labile mood, impulsivity, decreased need for sleep, and grandiosity. He was diagnosed with late-onset bipolar disorder after excluding other possible physiological conditions. He was hospitalized in the acute psychiatric ward, and a combination of mood stabilizers and antipsychotics was prescribed. His mental condition improved, and he remained stable for 2 years. However, he experienced abrupt cognitive decline for 2 months and was referred to the emergency room for physiological examination. Results. The patient was diagnosed with lung cancer with brain metastasis by brain magnetic resonance imaging and whole-body positron emission tomography. Conclusion. In geriatric patients, who are at high risk of multiple medical conditions, excluding secondary causes of bipolar disorder is important.http://dx.doi.org/10.1155/2021/8880539
spellingShingle Shin-Heng Shen
Shwu-Hua Lee
A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
Behavioural Neurology
title A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
title_full A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
title_fullStr A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
title_full_unstemmed A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
title_short A Case of Lung Cancer with Brain Metastasis following Late-Onset Bipolar Disorder
title_sort case of lung cancer with brain metastasis following late onset bipolar disorder
url http://dx.doi.org/10.1155/2021/8880539
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