ESBLs: A Clear and Present Danger?
Extended spectrum β-lactamases (ESBLs) are enzymes produced by a variety of Gram negative bacteria which confer an increased resistance to commonly used antibiotics. They are a worrying global public health issue as infections caused by such enzyme-producing organisms are associated with a higher m...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/625170 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850172570754613248 |
|---|---|
| author | Rishi H.-P. Dhillon John Clark |
| author_facet | Rishi H.-P. Dhillon John Clark |
| author_sort | Rishi H.-P. Dhillon |
| collection | DOAJ |
| description | Extended spectrum β-lactamases (ESBLs) are enzymes produced by a variety of Gram negative bacteria which confer an increased resistance to commonly used antibiotics.
They are a worrying global public health issue as infections caused by such enzyme-producing organisms are associated with a higher morbidity and mortality and greater fiscal burden. Coupled with increasing prevalence rates worldwide and an ever diminishing supply in the antibiotic armamentarium, these enzymes represent a clear and present danger to public health. This article aims to give an overview of the current situation regarding ESBLs, with a focus on the epidemiology and management of such infections. |
| format | Article |
| id | doaj-art-d008b58e75df44ad8164728bc25b85b3 |
| institution | OA Journals |
| issn | 2090-1305 2090-1313 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Critical Care Research and Practice |
| spelling | doaj-art-d008b58e75df44ad8164728bc25b85b32025-08-20T02:20:03ZengWileyCritical Care Research and Practice2090-13052090-13132012-01-01201210.1155/2012/625170625170ESBLs: A Clear and Present Danger?Rishi H.-P. Dhillon0John Clark1Department of Medical Microbiology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, Fulham Palace Road, London W6 8RF, UKEpsom and St Helier University Hospitals NHS Trust, Wrythe Lane, Carshalton, Surrey SM5 1AA, UKExtended spectrum β-lactamases (ESBLs) are enzymes produced by a variety of Gram negative bacteria which confer an increased resistance to commonly used antibiotics. They are a worrying global public health issue as infections caused by such enzyme-producing organisms are associated with a higher morbidity and mortality and greater fiscal burden. Coupled with increasing prevalence rates worldwide and an ever diminishing supply in the antibiotic armamentarium, these enzymes represent a clear and present danger to public health. This article aims to give an overview of the current situation regarding ESBLs, with a focus on the epidemiology and management of such infections.http://dx.doi.org/10.1155/2012/625170 |
| spellingShingle | Rishi H.-P. Dhillon John Clark ESBLs: A Clear and Present Danger? Critical Care Research and Practice |
| title | ESBLs: A Clear and Present Danger? |
| title_full | ESBLs: A Clear and Present Danger? |
| title_fullStr | ESBLs: A Clear and Present Danger? |
| title_full_unstemmed | ESBLs: A Clear and Present Danger? |
| title_short | ESBLs: A Clear and Present Danger? |
| title_sort | esbls a clear and present danger |
| url | http://dx.doi.org/10.1155/2012/625170 |
| work_keys_str_mv | AT rishihpdhillon esblsaclearandpresentdanger AT johnclark esblsaclearandpresentdanger |