Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome

Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome

Abstract Background Young, healthy women carrying a pathogenic or likely pathogenic variant (P/LPV) in genes configuring the hereditary breast and/or ovarian cancer (HBOC) syndrome face several non-oncological issues. Among these, the implications on fertility are not yet entirely understood. Method...

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Main Authors: Giovanna Sighinolfi, Giovanni Grandi, Elena Barbieri, Marta Venturelli, Claudia Piombino, Chiara Melotti, Rebecca Lippi Bruni, Riccardo Costantini Cuoghi, Roberto D’Amico, Matteo Lambertini, Fedro A. Peccatori, Elena Tenedini, Massimo Dominici, Laura Cortesi, Antonio La Marca, Angela Toss
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00788-9
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