Dysregulated interleukin networks drive immune heterogeneity in Alzheimer’s disease: an immunogenomic approach to subgroup classification and predictive modeling

Dysregulated interleukin networks drive immune heterogeneity in Alzheimer’s disease: an immunogenomic approach to subgroup classification and predictive modeling

Abstract Background Alzheimer’s Disease (AD) is marked by intricate immunological alterations, including the dysregulation of interleukin signaling. This study investigates the differential expression and potential roles of interleukins and their receptors in AD patients. Methods We analyzed the GSE...

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Bibliographic Details
Main Authors: Bin Zhang, Binglei Xu, Ruoxian Zhang, Baoying Gong, Jianwen Guo
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Neurology
Subjects:
Alzheimer's disease
Interleukins
Immune profiling
Predictive nomogram
Immune subtypes
Online Access:https://doi.org/10.1186/s12883-025-04155-y
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