Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery

Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery bet...

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Main Authors: Chunli Dong, Haozheng Yuan, Renyan Xu, Hui Zhang, Lili He, Weihong Qi, Xin Zhang
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2020-01-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/11747
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author Chunli Dong
Haozheng Yuan
Renyan Xu
Hui Zhang
Lili He
Weihong Qi
Xin Zhang
author_facet Chunli Dong
Haozheng Yuan
Renyan Xu
Hui Zhang
Lili He
Weihong Qi
Xin Zhang
author_sort Chunli Dong
collection DOAJ
description Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery between January 2016 and December 2017 were selected from two class-100 laminar flow ORs of equivalent area, and were divided into an experimental group and a control group. Results: The experimental group had significantly lower total air-borne bacterial count in the OR than the control group 10 minutes before surgery (6.21 ± 4.14 vs. 11.58 ± 5.36 CFU/cm3), 10 minutes (15.67 ± 6.21 vs. 20.83 ± 5.78 CFU/cm3), 30 minutes (27.34 ± 8.18 vs. 39.56 ± 7.86 CFU/cm3) and 60 minutes (43.62 ± 7.66 vs. 51.63 ± 8.43 CFU/cm3) into surgery, and at the end of surgery (57.34 ± 7.67 vs. 69.33 ± 9.41 CFU/cm3) (all p < 0.05). The incidence rates of increased body temperature and leukocyte count 3 days post-surgery, and the duration of antibiotic therapy and hospital stay were significantly reduced in the experimental group compared to the control group (all p < 0.05). Furthermore, the total number of pathogens in the incision at 2 hours into surgery was also significantly lower in the experimental group than in the control group (p < 0.05). Conclusion: Stringent application of the infection control pathway is an efficacious measure for improving the air cleanliness of the neurosurgery OR, decreasing the incidence rates of postoperative complications and infection, as well as controlling pathogen transmission.
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spelling doaj-art-cfe6f2c68fa348d7994c83490a01e0712025-08-20T02:57:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802020-01-01140110.3855/jidc.11747Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgeryChunli Dong0Haozheng Yuan1Renyan Xu2Hui Zhang3Lili He4Weihong Qi5Xin Zhang6Department of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Anesthesiology and Operation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery between January 2016 and December 2017 were selected from two class-100 laminar flow ORs of equivalent area, and were divided into an experimental group and a control group. Results: The experimental group had significantly lower total air-borne bacterial count in the OR than the control group 10 minutes before surgery (6.21 ± 4.14 vs. 11.58 ± 5.36 CFU/cm3), 10 minutes (15.67 ± 6.21 vs. 20.83 ± 5.78 CFU/cm3), 30 minutes (27.34 ± 8.18 vs. 39.56 ± 7.86 CFU/cm3) and 60 minutes (43.62 ± 7.66 vs. 51.63 ± 8.43 CFU/cm3) into surgery, and at the end of surgery (57.34 ± 7.67 vs. 69.33 ± 9.41 CFU/cm3) (all p < 0.05). The incidence rates of increased body temperature and leukocyte count 3 days post-surgery, and the duration of antibiotic therapy and hospital stay were significantly reduced in the experimental group compared to the control group (all p < 0.05). Furthermore, the total number of pathogens in the incision at 2 hours into surgery was also significantly lower in the experimental group than in the control group (p < 0.05). Conclusion: Stringent application of the infection control pathway is an efficacious measure for improving the air cleanliness of the neurosurgery OR, decreasing the incidence rates of postoperative complications and infection, as well as controlling pathogen transmission. https://jidc.org/index.php/journal/article/view/11747operating roompostoperative infectioninfection controlair cleanliness
spellingShingle Chunli Dong
Haozheng Yuan
Renyan Xu
Hui Zhang
Lili He
Weihong Qi
Xin Zhang
Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
Journal of Infection in Developing Countries
operating room
postoperative infection
infection control
air cleanliness
title Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
title_full Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
title_fullStr Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
title_full_unstemmed Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
title_short Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
title_sort efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery
topic operating room
postoperative infection
infection control
air cleanliness
url https://jidc.org/index.php/journal/article/view/11747
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AT renyanxu efficacyofinfectioncontrolpathwayinreducingpostoperativeinfectionsinpatientsundergoingneurosurgery
AT huizhang efficacyofinfectioncontrolpathwayinreducingpostoperativeinfectionsinpatientsundergoingneurosurgery
AT lilihe efficacyofinfectioncontrolpathwayinreducingpostoperativeinfectionsinpatientsundergoingneurosurgery
AT weihongqi efficacyofinfectioncontrolpathwayinreducingpostoperativeinfectionsinpatientsundergoingneurosurgery
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